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首页> 外文期刊>Frontiers in Surgery >Penile Rehabilitation and Treatment Options for Erectile Dysfunction Following Radical Prostatectomy and Radiotherapy: A Systematic Review
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Penile Rehabilitation and Treatment Options for Erectile Dysfunction Following Radical Prostatectomy and Radiotherapy: A Systematic Review

机译：根治性前列腺切除术后勃起功能障碍的阴茎康复和治疗方案：系统评价

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摘要

After radical prostatectomy (RP) or radiotherapy (RT) for prostate cancer, erectile dysfunction (ED) is the main complication next to urinary incontinence, affecting quality of life. The pathophysiology of ED after these treatments is believed to include neuropraxia causing reduced oxygenation and structural changes of the tissue in the corpora cavernosa. Next to the option of sparing the nerves during RP, research has been focusing on methods for penile rehabilitation after RP and RT, since it occurs often, even after nerve-sparing techniques were used. In animal studies, the use of phosphodiesterase type 5 inhibitors (PDE5i) after cavernous nerve damage is supported, but results in human studies are contradictory. Non-medical treatment options such as vacuum device therapy, hyperbaric oxygen therapy, yoga, aerobic, or pelvic floor training may be helpful, but evidence is scarce. Clear guidelines for penile rehabilitation are not yet available. However, care and support for ED after RP and RT is highly demanded by a large group of patients, so measures have to be taken even though the evidence is not strong yet. In this systematic review, an overview of the literature for penile rehabilitation and treatment options for ED after RP and RT is provided, using only randomized controlled trials (RCT).
机译：在激进前列腺切除术（RP）或放射治疗（RT）进行前列腺癌后，勃起功能障碍（ED）是尿失禁旁边的主要复杂性，影响生活质量。据信，ed的病理生理学据信包括神经养殖，导致Coramernosa中组织的氧合和结构变化。在选择RP期间保留神经的选择旁，研究一直专注于RP和RT后的阴茎康复方法，因为它通常发生，即使在使用神经备件技术之后。在动物研究中，支撑在海绵体神经损伤后使用磷酸二酯酶型5抑制剂（PDE5i），但是人类研究的结果是矛盾的。真空器材治疗，高压氧疗法，瑜伽，有氧或盆底训练等非医疗选择可能会有所帮助，但证据稀缺。明确的阴茎康复指南尚未提供。然而，大量患者的RP和RT在RP和RT之后进行护理和支持，因此即使证据尚不强劲，也必须采取措施。在该系统审查中，使用仅随机对照试验（RCT），提供RP和RT后ED的阴茎康复和治疗方案的文献概述。

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