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首页> 外文期刊>Substance Abuse Treatment, Prevention, and Policy >Prevalence and associated factors for alcohol use disorder among tuberculosis patients: a systematic review and meta-analysis study
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Prevalence and associated factors for alcohol use disorder among tuberculosis patients: a systematic review and meta-analysis study

机译：结核病患者中酒精使用障碍的患病率和相关因素：系统审查和荟萃分析研究

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Alcohol use disorders (AUD) in tuberculosis patients are complicated with poor compliance to anti-tuberculosis treatment and poor tuberculosis treatment outcomes. However, aggregate data concerning this problem is not available. Therefore, this review aimed to fill the above gap by generating an average prevalence of AUD in tuberculosis patients. Our electronic search for original articles was conducted in the databases of Scopus, PubMed, and EMBASE, African Index Medicus, and psych-info. Besides, the reference list of selected articles was looked at manually to have further eligible articles for the prevalence and associated factors of AUD in tuberculosis patients. The random-effects model was employed during the analysis. MS-Excel was used to extract data and stata-11 to determine the average prevalence of AUD among tuberculosis patients. A sub-group analysis and sensitivity analysis were also run. A visual inspection of the funnel plots and an Eggers publication bias plot test were checked for the presence of publication bias. A search of the electronic and manual system resulted in 1970 articles. After removing duplicates and unoriginal articles, only 28 articles that studied 30,854 tuberculosis patients met the inclusion criteria. The average estimated prevalence of AUD in tuberculosis patients was 30% (95% CI: 24.00, 35.00). This was with a slight heterogeneity (I2?=?57%, p-value ?0.001). The prevalence of AUD in tuberculosis patients was higher in Asia and Europe; 37% than the prevalence in the US and Africa; 24%. Besides, the average prevalence of AUD was 39, 30, 30, and 20% in studies with case-control, cohort, cross-sectional and experimental in design respectively. Also, the prevalence of AUD was higher in studies with the assessment tool not reported (36%) than studies assessed with AUDIT. AUD was also relatively higher in studies with a mean age of ≥40?years (42%) than studies with a mean age??40?years (24%) and mean age not reported (27%). Based on a qualitative review; the male gender, older age, being single, unemployment, low level of education and income from socio-demographic variables, retreatment and treatment failure patients, stigma, and medication non-adherence from clinical variables were among the associated factors for AUD. This review obtained a high average prevalence of AUD in tuberculosis patients and this varies across continents, design of studies, mean age of the participants, and assessment tool used. This implied the need for early screening and management of AUD in tuberculosis patients.
机译：结核病患者的酒精使用障碍（AUD）与抗结核病治疗较差和结核治疗结果差异不良。但是，有关此问题的聚合数据不可用。因此，本综述旨在通过在结核病患者的普及患者的普及患病患者中填补上述差距。我们的电子搜索原始文章是在Scopus，PubMed和Embase，African指数Medicus和Psych-Info的数据库中进行的。此外，所选文章的参考列表被手动查找，以便在结核病患者中具有进一步的符合条件的文章，患有患病率的患病率和相关因素。在分析期间使用随机效应模型。 MS-Excel用于提取数据和Stata-11，以确定结核病患者的患者的平均患病率。还运行亚组分析和敏感性分析。检查漏斗图和鸡蛋出版物偏差局部概率测试的目视检查是否存在出版物偏差。搜索电子和手动系统导致了1970篇文章。除去重复和无识别物品后，只有28篇学习30,854例结核病患者达到纳入标准。结核病患者的AUD的平均估计患病率为30％（95％CI：24.00,35.00）。这是具有轻微的异质性（I2？=Δ= 57％，p值<0.001）。亚洲和欧洲结核病患者的AUD患病率更高; 37％而不是美国和非洲的普遍存在; 24％。此外，分别在案例控制，队列，横截面和实验中的研究中，AUD的平均患病率为39,30,30和20％。此外，患有评估工具的研究患病率较高（36％）而不是通过审计评估的研究。患有平均年龄≥40岁的研究也比≥40岁的研究（42％）比具有平均年龄的研究（42％）？＆？40？岁（24％），平均未报告（27％）。基于定性审查;男性性别，年龄较大，单身，失业，社会人口变量的低位教育和收入低，后退和治疗失败患者，耻辱和药物从临床变量中不遵守患者是澳元的相关因素。本综述在结核病患者中获得了澳元的高平均患病率，这遍布大陆，研究设计，参与者的平均年龄和使用的评估工具。这暗示了在结核病患者的早期筛查和管理的需要。

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