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首页> 外文期刊>Journal of Clinical Sciences >Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study
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Pattern of postchemotherapy-associated complicatioins in a paediatric oncology service in Lagos: An observational study

机译：拉各斯儿科肿瘤服务中的培育疗法相关补偿的模式：观察学习

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Background: Globally, there is an increase in the number of pediatric oncology cases with significant morbidity and mortality in the low to middle income countries (LMIC) despite improved survival in the resource endowed nations. The increase in survival is largely due to the revolutionary use of multi strategy therapeutic interventions like chemotherapy, immunotherapy, surgery and radiotherapy. These modalities are however fraught with several complications. AIM The aim of this study was to prospectively observe and document the common complications following treatment of childhood cancers in a tertiary pediatric oncology unit in a resource constrained setting. Methods: This was a longitudinal observational study over a three-year period involving children with various cancers. Ethical approval was obtained from the hospital's human, research and ethics committee. A questionnaire was used to obtain socio-demographic data as well as details of adverse events encountered. Results: A total of 100 children enrolled in the study with acute lymphoblastic leukaemia been the commonest cancer. Gastrointestinal adverse events were the most common in the study cohort with alopecia rarely reported. Conclusion: Increased awareness of the common complications in this environment and prophylactic medications may improve the care of children post chemotherapy thereby reducing overall morbidity and cost of care.
机译：背景：在全球范围内，尽管资源纳入国家的生存，但低至中等收入国家（LMIC）的显着发病率和死亡率具有显着发病率和死亡率的程度增加。存活的增加主要是由于革命性使用多种策略治疗干预措施，如化疗，免疫疗法，手术和放射疗法。然而，这些模态具有几种并发症。目的这项研究的目的是在资源受限环境中潜在治疗第三节儿科肿瘤学单位中儿童癌症后的常见并发症。方法：这是一个纵向观察研究，涉及各种癌症的儿童的三年。从医院的人类，研究和道德委员会获得道德批准。调查问卷被用来获得社会人口统计数据以及遇到不良事件的细节。结果：急性淋巴细胞白血病的研究共纳入了100名儿童是最常见的癌症。胃肠不良事件是秃头群体的研究队列中最常见的是很少报道。结论：提高对这种环境中常见并发症的认识，预防药物可能会改善化疗后儿童的护理，从而降低了整体发病率和护理成本。

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