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首页> 外文期刊>Journal of Patient Safety & Quality Improvement >Intravenous Use of Metoclopramide and Sustained Hypotension: A Case Report
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Intravenous Use of Metoclopramide and Sustained Hypotension: A Case Report

机译：静脉内使用甲氧氯普胺和持续的低血压：案例报告

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Introduction: Transient hypotension has been commonly associated with metoclopramide hydrochloride, particularly with intravenous use. However, the risk of sustained hypotension that lasts for hours has not been previously associated with metoclopramide, except for one published case report. This case report is aimed at documenting the second case of unusual and serious sustained hypotension that lasted for more than six hours following rapid intravenous use of metoclopramide prescribed for the prevention of cesarean section delivery related intra/postoperative nausea and vomiting. Case Report: A 33-year-old gravida III and para II woman was admitted to a hospital for an elective cesarean section delivery with normal baseline blood pressure. Following metoclopramide 10 mg intravenous push administration, over 5-10 seconds, the mother encountered sustained hypotension (60/40 mmHg) that lasted for 120 minutes. After resuscitation, her blood pressure raised to 105/60 mmHg. However, after spinal anesthesia with bupivacaine hydrochloride, her diastolic arterial blood pressure dropped back again to 40 mmHg which persisted for about six hours post-operation. Upon investigation, the sustained hypotension was found to be probably related to inappropriate and rapid administration of intravenous bolus dose of metoclopramide hydrochloride that could have been prevented since it should be administered slowly over at least three minutes. Conclusion: The risk of metoclopramide-induced hypotension should not be underestimated as it sometimes might be much severe than the risk of nausea and vomiting that warrants immediate attention from healthcare professionals and program managers.
机译：介绍：瞬时低血压通常与盐酸氯丙普胺，特别是静脉注射使用。然而，除了一个公布的案例报告外，持续时间持续时间持续时间持续时间持续几小时的持续低血压缺失。本案例报告旨在记录第二种异常和严重持续的低血压，持续超过六个小时后持续超过6小时，后静脉静脉普罗酰胺用于预防剖宫产段递送相关内/术后恶心和呕吐。案例报告：一名33岁的雷达三世和第II妇女们被送入医院，为普通基线血压提供了一家选修剖宫分系。在甲酰氯丙酰胺10mg静脉内推送给药后，母亲遇到持续120分钟的持续低血压（60/40mmHg）。复苏后，她的血压升至105/60 mmHg。然而，在用盐酸盐鲸酸盐的麻醉之后，她的舒张动脉血压再次掉落至40mmHg，后持续约6小时。在调查后，发现持续的低血压可能与静脉丙酰胺盐酸甲酰胺盐酸盐的不恰当和快速管理有关，因为它应该在至少三分钟内缓慢施用。结论：甲氯普胺诱导的低血压的风险不应低估，因为它有时可能比恶心和呕吐的风险严重，认证医疗保健专业人士和计划经理的立即关注。

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