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首页> 外文期刊>Journal of General and Family Medicine >An impact of dietary intervention on blood pressures among diabetic and/or hypertensive patients with high cardiovascular disorders risk in northern Thailand by cluster randomized trial
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An impact of dietary intervention on blood pressures among diabetic and/or hypertensive patients with high cardiovascular disorders risk in northern Thailand by cluster randomized trial

机译:膳食干预对泰国北北部患有高心血管障碍风险的血管和/或高血压患者血压的影响

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Background Global sodium intake remains above the recommended levels to control blood pressure (BP). We aimed to evaluate the efficacy of a dietary intervention on BP through salt reduction among community‐dwelling participants with high risk of cardiovascular disorders (CVD). Methods This cluster randomized trial (February 2012 to January 2013) included cooking instruction using the pocket salt meter among patients with diabetes and/or hypertension who were treated at health center in Thailand. Based on health centers, 8 clusters of eligible participants were randomly allocated to the 4 intervention and 4 control groups. Dietary intervention was performed at baseline, 1?month, and 3?months in intervention group. In both groups, systolic and diastolic BPs, and estimated 24?hours salt intake based on overnight urine samples were measured at baseline, 6?months, and 12?months. Results A total of 753 participants were enrolled (374 in the intervention group and 379 in the control group). In the mixed‐effects model, there were significant difference in SBP and estimated salt intake after adjusting covariates at 6?months (adjusted differences between groups [95% CI]; ?7.55 [?5.61 to ?9.49] mm?Hg P ?.01; ?0.66 [?0.40 to ?0.92] g/day P =?.03). However, these differences were not observed at 12?months (adjusted differences between groups [95% CI]; ?1.83 [0.34 to ?4.00] mm?Hg P =?.48; ?0.42 [?0.17 to ?0.67] g/day P =?.16). There were no differences in DBP in both follow‐ups. Conclusions These results may suggest the effectiveness of a visually based dietary intervention targeting salt intake reduction in short term, but the effectiveness discontinued in long term. Clinical trial number: The International Standard Randomized Controlled Trial Number Register (ISRCTN39416277) on January 3, 2012.
机译:背景技术全局钠摄入量仍然高于推荐的水平以控制血压(BP)。我们旨在评估膳食干预对BP的疗效,通过含有高风险的心血管障碍(CVD)的社区住宅参与者。方法采用该集群随机试验(2012年2月至2013年1月)包括使用糖尿病和/或高血压患者的口袋盐表的烹饪指示,他在泰国的保健中心治疗。基于健康中心,将8个合格参与者随机分配给4个干预和4个控制组。饮食干预在基线,1?月和3个月内进行干预组。在两组,基于一夜之间尿液样本的基准,6?个月,12个月,估计基于一夜之间的尿液样品,估计24次盐酸盐,并估计了24小时。结果共有753名参与者注册了753名参与者(374,在控制组中379年)。在混合效应模型中,在调整6?月份调节协变量后SBP和估计的盐摄入量有显着差异(分组之间调整差异[95%CI];α.7.55[α.5.61至α.99] mm。Hg p& ?.01;?0.66 [?0.40至0.92] G /天P = 03)。然而,在12?月份未观察到这些差异(组之间的调节差异[95%];?1.83 [0.34至4.00] mm?Hg p =α.48;?0.42 [〜017至0.67] g /天p = 16)。两种后续的DBP都没有差异。结论这些结果可能表明靶向膳食干预的有效性靶向含盐的盐疗法,但长期停止的有效性。临床试验编号:2012年1月3日的国际标准随机对照试验编号寄存器(ISRCTN39416277)。

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