...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Cureus. >Combined Diagnostic Accuracy of Total Leukocyte Count, Neutrophil Count, and Ultrasonography for the Diagnosis of Acute Appendicitis
【24h】

Combined Diagnostic Accuracy of Total Leukocyte Count, Neutrophil Count, and Ultrasonography for the Diagnosis of Acute Appendicitis

机译：总白细胞计数，中性粒细胞计数和超声诊断诊断急性阑尾炎的诊断诊断准确性

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Acute appendicitis is a common surgical emergency that classically presents with right lower abdominal pain and tenderness on palpation. The diagnosis is often based?on clinical examination in order to avoid the complications of surgery delay, yielding a high rate of negative appendectomies. Ultrasonography is a regularly used modality?for establishing the diagnosis, whereas abdominal computed tomography (CT) is often used in sonologically equivocal cases. Other parameters include?total leukocyte count, granulocytes, C-reactive protein (CRP), leukocyte elastase activity, D-lactate, phospholipase A2, and interleukin-6 (IL-6). We conducted a prospective study to assess the combined?accuracy of total leukocyte count, neutrophil count, and ultrasound as an integrated diagnostic tool. The results of these investigations?were tabulated and compared to histopathological evidence of acute appendicitis on biopsy (taken as the gold standard) to calculate sensitivity, specificity, positive?predictive?value, and negative?predictive value. Combined sensitivity and specificity were calculated using cross-tabulation, whereas diagnostic accuracy?was estimated from the receiver operating curve (ROC) at the optimal cut-off point. The results showed that the absence of inflammatory findings on ultrasound and normal blood parameters (total leukocyte count and neutrophil count) have a high combined diagnostic accuracy and appendicitis may be ruled out.
机译：急性阑尾炎是一种常见的外科急诊，典型伴随着右下腹痛和触诊的柔软。诊断通常是基于？在临床检查上，以避免手术延迟并发症，产生高率的阴性阑尾切除术。超声检查是一种定期使用的模态？用于建立诊断，而腹部计算断层扫描（CT）通常用于超声诊断。其他参数包括α总白细胞计数，粒细胞，C-反应蛋白（CRP），白细胞弹性蛋白酶活性，D-乳酸，磷脂脂酶A2和白细胞介素-6（IL-6）。我们进行了一项前瞻性研究，以评估总白细胞计数，中性粒细胞计数，中性粒细胞计数和超声的准确性作为综合诊断工具。这些调查的结果？与急性阑尾炎的组织病理学证据表明并与活组织检查（作为金标准）的组织病理学证据进行比较，以计算敏感性，特异性，阳性？预测？值和负数？预测值。使用交叉制表计算组合的敏感性和特异性，而诊断精度是在最佳截止点处的接收器操作曲线（ROC）估计。结果表明，超声波和正常血液参数（总白细胞计数和中性粒细胞计数）没有炎症发现具有高综合诊断准确性，并且可以排除阑尾炎。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号