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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Iodine concentration and prevalence of thyroid disease in older people after salt iodization in Turkey
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Iodine concentration and prevalence of thyroid disease in older people after salt iodization in Turkey

机译：土耳其盐碘化后老年人碘浓度和甲状腺疾病患病率

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Background: Iodine uptake is a main factor affecting thyroid disease. In Turkey, mandatory salt iodization began in 1999–2000. Aims: This study in 2009 determined the prevalence of thyroid diseases in older people in Mamak district, Ankara after iodization to ascertain if salt iodization alone is sufficient to reach adequate iodine levels in the older population. Methods: All Mamak residents ≥ 65 years were eligible for inclusion in the study. Demographic data and medical history were recorded. All participants had a thyroid ultrasound. Blood samples were taken to assess thyroid function and autoantibodies, and urine samples to assess iodine concentration. Participants with low levels of thyroid stimulating hormone underwent scintigraphy to assess thyroid uptake. Fine-needle aspiration biopsy was done of nodules ≥ 1.5 cm where thyroid stimulating hormone was not suppressed. Results: Of 1200 eligible residents, 979 were included. Their mean age was 70.9 (standard deviation (SD) 5.7) years; 49.7% were women. Mean urinary iodine concentration was 98 (SD 81.29) μg/L. Goitre was found in 18.2% (89/487) of women and 6.7% (33/492) of men (P 0.001) and 43.8% (428/979) had nodules. Subclinical hypothyroidism was found in 5.8% (57/979) of the participants, overt hyperthyroidism in 0.8% (8/979), subclinical hyperthyroidism in 2.2% (22/979) and T3 thyrotoxicosis in 0.3% (3/979). Toxic multinodular goitre and toxic adenoma caused 80% of hyperthyroidism cases. Biopsy detected no malignant pathology. Conclusion: After salt iodization, iodine levels have not yet reached favourable levels in older people. Iodization of salt seems insufficient to achieve these levels in older people; alternative iodine supplementation should be considered.
机译：背景：碘摄取是影响甲状腺疾病的主要因素。在土耳其，强制性盐碘化于1999年至2000年开始。目的：2009年的这项研究确定了碘化的玛雅地区老年人甲状腺疾病的患病率，以确定单独盐碘化是否足以达到老年人口的足够碘水平。方法：所有Mamak居民≥65年都有资格纳入该研究。记录人口统计数据和病史。所有参与者都有一个甲状腺超声波。采用血液样品评估甲状腺功能和自身抗体，尿液样品评估碘浓度。甲状腺水平低水平刺激激素的参与者接受了闪烁的吸附来评估甲状腺吸收。细针吸入活检是结节≥1.5cm的，其中甲状腺刺激激素未被抑制。结果：1200个符合条件的居民，包括979个。他们的平均年龄为70.9（标准差（SD）5.7）岁; 49.7％是女性。平均尿碘浓度为98（SD 81.29）μg/ L. GoItre于18.2％（89/487）妇女，6.7％（33/492）男性（P <0.001），43.8％（428/979）有结节。在5.8％（57/979）的参与者中发现了亚临床甲状腺功能减退症，公开甲状腺功能亢进症在0.8％（8/979），亚临床甲状腺功能亢进中，在2.2％（22/979）和T3甲状腺毒性0.3％（3/979）中。有毒多型巨型和有毒腺瘤引起了80％的甲状腺功能亢进病例。活检检测到没有恶性病理学。结论：盐碘化后，碘水平尚未达到老年人的有利水平。盐的碘化似乎不足以在老年人中达到这些水平;应考虑替代碘补充剂。

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