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首页> 外文期刊>Endocrinology, Diabetes & Metabolism >The Effect of Thyroid?Stimulating Hormone on Stage of Differentiated Thyroid Carcinoma
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The Effect of Thyroid?Stimulating Hormone on Stage of Differentiated Thyroid Carcinoma

机译：甲状腺的作用？刺激甲状腺癌阶段刺激激素

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Introduction Thyroid cancer is the most common endocrine malignancy, and it has the fastest increase rate in incidence in both sexes, with a yearly increase of 3% over the last decade. Thyroid-stimulating hormone (TSH) is the main driver for the thyroid gland to produce thyroid hormone. The main purpose of this study was to assess the relationship between serum TSH level and the stage of malignancy in patients with differentiated thyroid cancer. Methods This cross-sectional study was performed on 77 patients with thyroid cancer. The demographic characteristics, TSH level and stage of malignancy were recorded for all patients in the data collection form. The data analysis was conducted by descriptive statistics using SPSS 20.0 software. Results The results show a significant relationship ( p -value?=?.025) between the malignancy stage and serum TSH level. The mean TSH level in patients of stage 3 (5.70?±?2.03) was significantly higher than patients in stage 2 (2.58?±?0.52) and stage 1 (2.33?±?0.28). No significant relationship was observed between the age of patients and serum TSH level. Although the mean serum TSH level in men (3.61?±?0.98) was higher than in women (2.52?±?0.25), the difference was not statistically significant. Conclusions According to the results of this study, serum TSH level can be considered as a predictor of the stage of differentiated thyroid cancer. Therefore, it can be used to predict the likelihood of cancer and improve the outcome and extent of thyroidectomy in patients with thyroid cancer.
机译：引言甲状腺癌是最常见的内分泌恶性肿瘤，它在两性的发病率增加最快，在过去十年中每年增加3％。致甲状腺激素（TSH）是甲状腺产生甲状腺激素的主要驱动器。本研究的主要目的是评估血清TSH水平与分化甲状腺癌患者的恶性肿瘤阶段之间的关系。方法对77例甲状腺癌患者进行这种横截面研究。为数据收集表格中的所有患者记录了恶性肿瘤的人口特征，TSH水平和阶段。使用SPSS 20.0软件通过描述性统计进行数据分析。结果结果表明，恶性阶段和血清TSH水平之间的显着关系（p-value？=Δ.025）。第3阶段（5.70？±2.03）患者的平均TSH水平明显高于第2阶段（2.58？±0.52）和第1阶段（2.33？±0.28）的患者。在患者年龄和血清TSH水平之间没有观察到明显的关系。虽然男性的平均血清TSH水平（3.61？±0.98）高于女性（2.52？±0.25），但差异没有统计学意义。结论根据本研究的结果，血清TSH水平可以被认为是分化甲状腺癌阶段的预测因子。因此，它可用于预测癌症的可能性，并改善甲状腺癌患者的甲状腺切除术的结果和程度。

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