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首页> 外文期刊>Endocrinology, Diabetes & Metabolism >The Impact of COVID-19 Pandemic on Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: A Single-Centre Study in Central Pennsylvania
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The Impact of COVID-19 Pandemic on Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: A Single-Centre Study in Central Pennsylvania

机译：Covid-19大流行对1型糖尿病诊断糖尿病酮症病的影响：宾夕法尼亚中部的单中心研究

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Objective We conducted this study to investigate whether the COVID-19 pandemic impacted the rate of DKA and previously identified risk factors in children presenting with T1D. Methods We performed an extension of a retrospective analysis of all paediatric patients (age?≤?18) newly diagnosed with T1D within a tertiary care referral centre between 01/01/2017 and 09/14/2020. Demographics, insurance coverage and clinical documents 30?days before their T1D diagnosis were abstracted to assess for?symptoms at diagnosis,?laboratory values (blood glucose, HbA 1c , venous pH and bicarbonate) and any healthcare encounters within 30?days of their diagnosis of T1D. Results 412 patients with T1D [171 F:241?M; 370 pre-COVID era:42 post-COVID era] were included. The percentages of DKA diagnoses at admission were very similar between the pre-COVID and post-COVID groups (47% vs. 48%), as were the severity (13% vs. 14% mild DKA; 33% vs. 31% moderate or severe DKA). Conclusion There were no fluctuations in the rate of DKA among paediatric patients newly diagnosed with T1D throughout the coronavirus pandemic in central Pennsylvania.
机译：目的我们进行了这项研究，以调查Covid-19大流行是否影响了DKA的速度和先前确定了患有T1D的儿童的风险因素。方法我们对所有儿科患者（年龄≤α18）进行了回顾性分析的延长，所述患者在第01/01/01/01/01/14/2020之间进行三级护理推荐中心内进行新诊断的T1D。人口统计数据，保险范围和临床文献30？他们的T1D诊断前的天数被抽象为诊断症状，？实验室价值（血糖，HBA 1C，静脉pH和碳酸氢盐）和30个诊断时间内的任何医疗保健遭遇T1D。结果412例T1D患者[171 F：241吗？包括370套餐时代：42个后Covid时代]。在核心前的患者和核糖酰基和后核苷酸基团之间（47％对48％）之间的百分比百分比非常相似，因此严重程度（13％对14％轻度DKA; 33％与31％中等或严重的DKA）。结论在宾夕法尼亚州中部冠心病大流行病中新诊断出T1D的儿科患者中DKA的速度没有波动。

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