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首页> 外文期刊>GaBi journal. >Microbiological, scientific and regulatory perspectives of hand sanitizers
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Microbiological, scientific and regulatory perspectives of hand sanitizers

机译：手动消毒剂的微生物，科学和监管角度

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摘要

Hand sanitizers are rub-on formulations for the purpose of inactivating microorganisms on the hands. With the recent COVID-19 pandemic, a surge in the manufacturing, sale and use of hand sanitizers is observed. However, the effectiveness and safety of hand sanitizers are not well understood by the public; thus, hand sanitizer usage may not confer adequate protection and may pose safety threats. Globally, the emergence of safety threats and inappropriate manufacturer claims also suggest that regulatory frameworks are insufficient in ensuring optimal effectiveness and safety standards for hand sanitizers. This paper presents an overview of the activity of antimicrobials as active ingredients in hand sanitizers and the principles of test methods to evaluate the effectiveness of hand sanitizers. Different antimicrobials confer different activities, rendering some more useful than others. There are also no specific compendial test for efficacy of hand sanitizers and the choice of test method is left to the discretion of manufacturers. It has also been reported that a significant number of hand sanitizers were improperly labelled or had inappropriate claims. Implementing a tighter regulatory framework, developing pharmacists’ knowledge and capabilities, raising consumer awareness and debunking common myths are some possible solutions to address the problems encountered.
机译：手动消毒剂是摩擦配方，以便在手上灭活微生物。随着最近的Covid-19大流行，观察到制造，销售和使用手动消毒剂的浪涌。然而，公众的手动消毒剂的有效性和安全性并不是很好地理解;因此，手动消毒剂使用可能无法赋予足够的保护，并且可能构成安全威胁。在全球范围内，安全威胁的出现和不适当的制造商声称还表明，监管框架在确保手动消毒剂的最佳效率和安全标准方面不足。本文概述了抗微生物活性作为手动消毒剂的活性成分的活性以及评估手动消毒剂有效性的试验方法的原理。不同的抗菌剂赋予不同的活动，使一些比其他活动更有用。还没有针对手动消毒剂的功效的特定竞选测试，并选择测试方法的选择是制造商的自由裁量权。据报道，大量的手动消毒剂被认为是不正确的标记或未恰当的索赔。实施更严格的监管框架，制定药剂师的知识和能力，提高消费者的意识和揭穿普通神话是解决遇到的问题的一些可能的解决方案。

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