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Changes in insomnia as a risk factor for the incidence and persistence of anxiety and depression: a longitudinal community study

机译:失眠变化作为焦虑和抑郁发病率和持续存在的危险因素:纵向社区研究

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Background The aim of this investigation was to examine the longitudinal association between change in insomnia status and the development of anxiety and depression in the general population. Methods A survey was mailed to 5000 randomly selected individuals (aged 18–70?years) in two Swedish counties. After 6 months, a follow-up survey was sent to those ( n =?2333) who answered the first questionnaire. The follow-up survey was completed by 1887 individuals (80.9%). The survey consisted of questions indexing insomnia symptomatology, socio-demographic parameters, and the Hospital Anxiety and Depression Scale. Change in insomnia status was assessed by determining insomnia at the two time-points and then calculating a change index reflecting incidence (from non-insomnia to insomnia), remission (from insomnia to non-insomnia), or status quo (no change). Multivariate binary logistic regression analyses were used to examine the aim. Results Incident insomnia was significantly associated with an increased risk for the development of new cases of both anxiety (OR?=?0.32, p ?.05) and depression (OR?=?0.43, p ?.05) 6?months later. Incident insomnia emerged also as significantly associated with an elevated risk for the persistence of depression (OR?=?0.30, p ?.05), but not for anxiety. Conclusions This study extends previous research in that incidence in insomnia was shown to independently increase the risk for the development of anxiety and depression as well as for the maintenance of depression. The findings imply that insomnia may be viewed as a dynamic risk factor for anxiety and depression, which might have implications for preventative work.
机译:背景技术这一调查的目的是研究失眠状态变化与一般人群焦虑和抑郁症之间的纵向关联。方法将调查邮寄到两名瑞典县的5000名随机选择的个人(年龄18-70岁)。 6个月后,向那些回答第一个调查问卷的人(n = 2333)送出后续调查。后续调查由1887人(80.9%)完成。该调查包括索引失眠症症状,社会人口统计学参数和医院焦虑和抑郁症的问题。通过在两个时间点测定失眠,然后计算反映的变化指数(从非失眠症到失眠),缓解(从失眠到非失眠症),或现状(没有变化),评估失眠症状态的失眠状态。多变量二进制逻辑回归分析用于检查目的。结果事件失眠与发育焦虑的新病例的风险显着相关(或?= 0.32,P& 05)和抑郁症(或?=Δ0.43,p&。05)6 ?几个月后。事件失眠也出现了与抑郁症持续存在的危险性升高(或?= 0.30,P& 05)显着相关,但不是焦虑。结论本研究延长了以前的研究,因为令人独立地增加了失眠症的发病率,以焦虑和抑郁症的发展以及维持抑郁症的风险。研究结果意味着失眠可能被视为焦虑和抑郁的动态危险因素,这可能对预防性工作产生影响。

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