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首页> 外文期刊>Journal of surgery and medicine. >Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit
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Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit

机译：血小板减少症及其对重症监护单位死亡率和发病率的影响

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Background/Aim: Thrombocytopenia is a common hematological abnormality among patients in the intensive care unit (ICU). The development of thrombocytopenia in the ICU usually indicates severe organ system dysfunction rather than a primary hematological disorder. We aimed to determine the incidence, causes, and clinical results of thrombocytopenia in patients followed up in ICU. Methods: In this retrospective cohort study, 165 patients who were followed up in the ICU with thrombocyte counts below 150,000 /uL were included and causes of thrombocytopenia, along with its effects on mortality and intensive care stay were investigated. Results: Thrombocytopenia was determined in 30.1% of the patients in the ICU. The cause of thrombocytopenia was sepsis in 33 (20.0%) of the patients and disseminated intravascular coagulation (DIC) in 20 (12.1%) patients. During the study period, 115 (69.7%) of 165 thrombocytopenic patients and 173 (45.1%) of 383 patients without thrombocytopenia died. Mortality was significantly higher in patients with thrombocytopenia. Mortality significantly increased when platelet count decreased, even with similar APACHE II scores. Conclusion: The most common causes of thrombocytopenia in the ICU were sepsis and DIC. Thrombocytopenia is common in the ICU and increases mortality rates.
机译：背景/目的：血小板减少症是重症监护病房（ICU）中患者常见的血液学异常。 ICU中血小板减少症的发展通常表明严重的器官系统功能障碍而不是一次血液疾病。我们旨在确定血小板减少症在ICU的血小板减少症的发病率，原因和临床结果。方法：在这种回顾性队列研究中，包括血小板计数低于150,000 / UL的ICU的165名患者，并调查了血小板减少症的原因，以及其对死亡率和重症监护入住的影响。结果：血小板减少症在ICU中的30.1％患者中测定。血小板减少症的原因是33例（20.0％）患者的败血症，并在20名（12.1％）患者中弥散血管内凝血（DIC）。在研究期间，115名（69.7％）165名血小板减薄患者和173名（45.1％）的383名没有血小板减少症的患者死亡。血小板减少症患者的死亡率显着高。当血小板计数减少时，死亡率显着增加，即使具有类似的Apache II评分。结论：ICU中血小板减少症最常见的原因是脓毒症和DIC。血小板减少症在ICU中很常见，增加死亡率。

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