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Realistic Kidney Simulation for the Development of Renal Function Diagnostics by Dynamic SPECT Imaging

机译:现实的肾脏模拟动态SPECT成像开发肾功能诊断

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Dynamic SPECT imaging captures the dynamic process of the radioisotope washed in and out, to and from tissues and exchanged between biological compartments. One of the most common application field for dynamic SPECT imaging is investigating renal functions. The main goal of this study was to create realistic simulations of the kidney in order to support the development of dynamic SPECT reconstruction algorithms. We created and parametrized a compartment model of the kidney for simulating the dynamic behavior of the MAG3 radiopharmacon. Solving the model with a parameter set corresponding to the normal and to the pathological cases the SPECT data acquisition was simulated using the GATE Monte Carlo simulation toolkit.
机译:动态SPECT成像捕获放射性同位素的动态过程,进出组织,并在生物隔室之间交换。 动态SPECT成像最常见的应用领域之一正在调查肾功能。 本研究的主要目标是创造肾脏的现实模拟,以支持动态SPECT重建算法的发展。 我们创建和参数化了肾脏的隔间模型,用于模拟Mag3放射性手提片的动态行为。 用对应于正常的参数集和病理情况求解模型,使用门蒙特卡罗模拟工具包进行模拟SPECT数据采集。

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