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Model-based Patient Matching for in-parallel Multiplexing Mechanical Ventilation Support

机译:基于模型的患者匹配,用于平行多路复用机械通风支撑

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Surges of COVID-19 infections could lead to insufficient supply of mechanical ventilators, and rationing of needed care. Multiplexing mechanical ventilators (co-MV) to serve multiple patients is a potential temporary solution. However, if patients are ventilated in parallel ventilation, there is currently no means to match ventilation requirements or patients, with no guidelines to date for co-MV. This research uses patient-specific clinically validated respiratory mechanics models to propose a method for patient matching and mechanical ventilator settings for two-patient co-MV under pressure control mode. The proposed method can simulate and estimate the resultant tidal volume of different combinations of co-ventilated patients. With both patients fulfilling the specified constraint under similar ventilation settings, the actual mechanical ventilator settings for co-MV are determined. This method allows clinicians to analyze in silico co-MV before clinical implementation.
机译:Covid-19感染的浪涌可能导致机械通风机供应不足,以及所需护理的配给。 多路复用机械通风机(CO-MV)为多名患者提供服务是潜在的临时解决方案。 但是,如果患者在并联通风中通风,则目前没有匹配通风要求或患者的方法,没有迄今为止迄今为止的准则。 本研究采用患者特定的临床验证的呼吸力学模型提出了一种在压力控制模式下为双患者CO-MV进行患者匹配和机械通风机设置的方法。 所提出的方法可以模拟和估计相应患者的不同组合的所得潮量。 对于在类似的通风设置下满足指定约束的两种患者,确定了CO-MV的实际机械通风机设置。 这种方法允许临床医生在临床实施之前在硅CO-MV中分析。

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