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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Prospective Observational Study of Short-term Mortality Indicators in Acute Stroke Patients
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A Prospective Observational Study of Short-term Mortality Indicators in Acute Stroke Patients

机译：急性中风患者短期死亡率指标的前瞻性观察研究

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Stroke is the second leading cause of death worldwide, causing 6.2 million deaths in 2011. There is a lack of uniform consensus regarding the predicting factors for mortality associated with stroke.Aim: To determine the various factors which influence the mortality in acute stroke.Materials and Methods: This was a prospective study conducted between November 2017 to February 2020 at the hospitals attached to Bangalore Medical College and Research Institute, Bangalore, Karnataka, India. All the patients diagnosed with Cerebrovascular Accident (CVA) using neuroimaging of brain within 24 hours of a symptoms were enrolled and followed-up for 28 days. After obtaining informed consent, demographic, clinical, laboratory and radiological data was recorded. Patients were assessed using standardised data sheet containing different variables and treated appropriately for ischaemic and haemorrhagic stroke.Results: The study included 100 patients; 33 died during followup. The mean age of the patients was 55.35±15.78 years; there were 54 males and 46 females. Male gender (p-value <0.001), poor Glasgow Coma Scale (GCS) (p-value <0.001), severe neurodeficit (p-value <0.001), raised intracranial pressure (p-value <0.001) and complication like delayed recovery of GCS (p-value <0.001), aspiration pneumonia (p-value<0.001), Acute Kidney Injury (AKI) (p-value <0.001), fever (p-value <0.001), dysphagia (p-value <0.001), bedsore (p-value <0.001) and seizure (p-value <0.001) were the predictors of mortality in acute stroke.Conclusion: The factors like poor GCS, severe neurodeficit, raised intracranial pressure at the time presentation of patient and occurrence of complication like delayed recovery of GCS, aspiration pneumonia, AKI, fever, dysphagia, bedsore and seizure can be used as prognostic marker in acute stroke. Comprehensive neurological care wherever feasible involving neurologist, neurosurgeon, interventional radiologist, physiotherapist which take care of the immediate need and to prevent the long term complication would help to decrease mortality in acute stroke.
机译：中风是全世界第二次死亡原因，2011年造成620万人死亡。关于与中风有关的死亡率的预测因素缺乏统一的共识：确定影响急性中风中死亡率的各种因素。方法：这是2017年11月至2020年12月在班加罗尔医学院和研究所，班加罗尔，卡纳塔卡，印度班加罗尔的医院进行的一项潜在研究。所有患有脑血管事故（CVA）的患者在症状的24小时内使用脑内脑的神经模仿，并进行28天。在获得知情同意后，记录了人口统计学，临床，实验室和放射性数据。使用含有不同变量的标准化数据片进行评估，并适当地治疗缺血性和出血性脑卒中。结果包括100名患者; 33在后续期间死亡。患者的平均年龄为55.35±15.78岁;有54名男性和46名女性。男性性别（P值<0.001），Glasgow Coma Scale（GCS）差（P值<0.001），严重的神经缺陷（P值<0.001），提高颅内压（P值<0.001）并复杂化如延迟恢复GCS（P值<0.001），抽吸肺炎（p值<0.001），急性肾损伤（aki）（p值<0.001），发热（p值<0.001），吞咽困难（p值<0.001 ），褥疮（P值<0.001）和癫痫发作（p值<0.001）是急性中风中死亡率的预测因子。结论：贫困GCS，严重的神经缺乏，患者患者的颅内压力等因素与GCs的延迟回收一样，患有GCS，抽吸肺炎，发烧，吞咽，困难，褥疮和癫痫发作的并发症可以用作急性中风中的预后标志物。综合神经医疗无需涉及神经培训，神经外科医生，介入放射科医生，治疗即时需求的物理治疗师，并防止长期并发症会有助于降低急性中风的死亡率。

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