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首页> 外文期刊>Indian Journal of Critical Care Medicine >A New ICU Delirium Prevention Bundle to Reduce the Incidence of Delirium: A Randomized Parallel Group Trial
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A New ICU Delirium Prevention Bundle to Reduce the Incidence of Delirium: A Randomized Parallel Group Trial

机译:新的ICU谵妄预防捆绑捆绑,以减少谵妄的发病率:随机并联组试验

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Introduction:Although various preventive strategies have been advocated, delirium is common in critically ill patients and is associated with increased morbidity, mortality, and long-term adverse effects. The efficacy of a novel delirium prevention bundle in mechanically ventilated critically ill patients was investigated in this study.Methods:In this randomized controlled trial, 50 mechanically ventilated adult patients in a tertiary care medical-surgical intensive care unit (ICU) were randomized to receive either delirium prevention bundle protocol or standard of care protocol. Delirium was assessed daily using the Confusion Assessment Method for the ICU (CAM-ICU) score by an independent investigator up to 28 days or death or discharge. The primary outcome was the incidence of new-onset delirium. Secondary outcomes were duration of mechanical ventilation, ICU length of stay (ICU-LOS), hospital LOS, and other adverse events.Results:There was a 20% reduction in the incidence of delirium in the intervention group (36 vs 56%; p = 0.156). The 28-day mortality (28 vs 24%; p = 0.747), duration of mechanical ventilation (9 vs 12 days; p = 0.281), ICU-LOS (11 vs 12 days; p = 0.221), and hospital LOS (16 vs 20 days; p = 0.062) were similar between the groups.Conclusion:Implementation of delirium prevention bundle does not reduce the incidence of delirium compared to standard of care protocol in mechanically ventilated critically ill patients.How to cite this article:Malik AK, Baidya DK, Anand RK, Subramaniam R. A New ICU Delirium Prevention Bundle to Reduce the Incidence of Delirium: A Randomized Parallel Group Trial. Indian J Crit Care Med 2021;25(7):754-760.Copyright ? 2021; Jaypee Brothers Medical Publishers (P) Ltd.
机译:介绍:虽然倡导各种预防策略,但谵妄在危重病患者中常见,并且与发病率,死亡率和长期不良反应有关。本研究研究了新型谵妄预防束的疗效。在本研究中,研究了以下方法:在该随机对照试验中,在第三节护理医疗 - 外科重症监护病房(ICU)中,50名机械通风的成年患者随机接受谵妄预防捆绑捆绑协议或护理方案标准。每天评估谵妄每天评估ICU(CAM-ICU)的混乱评估方法,由独立调查员得分,长达28天或死亡或排放。主要结果是新发病谵妄的发病率。二次结果是机械通气的持续时间,ICU住宿时间(ICU-LOS),医院洛杉矶和其他不利事件。结果:干预组谵妄发病率降低了20%(36 vs 56%; p = 0.156)。 28天死亡率(28 vs 28%; p = 0.747),机械通气持续时间(9 vs 12天; p = 0.281),ICU-LOS(11 vs 12天; P = 0.221)和医院LOS(16 vs 20天; p = 0.062)在组之间类似。结论:谵妄预防捆绑包的实施不会降低与机械通风批评患者的护理方案标准相比谵妄的发生率。为了引用本文:Malik Ak, Baidya DK,Anand RK,Subramaniam R.新的ICU谵妄预防捆绑包,以减少谵妄的发病率:随机并联组试验。印度j crit care med 2021; 25(7):754-760.copyright? 2021; Jaypee Brothers Medical Publishers(P)有限公司

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