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首页> 外文期刊>Trials >COVEPIC (Cognitive and spOrt Virtual EPIC training) investigating the effects of home-based physical exercise and cognitive training on cognitive and physical functions in community-dwelling older adults: study protocol of a randomized single-blinded clinical trial
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COVEPIC (Cognitive and spOrt Virtual EPIC training) investigating the effects of home-based physical exercise and cognitive training on cognitive and physical functions in community-dwelling older adults: study protocol of a randomized single-blinded clinical trial

机译：CoVepic（认知和体育虚拟史诗训练）调查家庭体育运动和认知培训对社区住宅老年人认知和身体功能的影响：随机单盲临床试验的研究方案

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In the context of the COVID-19 pandemic, lockdown and social distancing measures are applied to prevent the spread of the virus. It is well known that confinement and social isolation can have a negative impact on physical and mental health, including cognition. Physical activity and cognitive training can help enhance older adults’ cognitive and physical health and prevent the negative collateral impacts of social isolation and physical inactivity. The COVEPIC study aims to document the effects of 6?months of home-based physical exercise alone versus home-based physical exercise combined with cognitive training on cognitive and physical functions in adults 50?years and older. One hundred twenty-two healthy older adults (?50?years old) will be recruited from the community and randomized to one of the two arms for 6?months: (1) home-based physical exercises monitoring alone and (2) combined physical exercises monitoring with home-based cognitive training. The primary outcome is cognition, including general functioning (Montreal Cognitive Assessment (MoCA) score), as well as executive functions, processing speed, and episodic memory (composite Z-scores based on validated neuropsychological tests and computerized tasks). The secondary outcome is physical functions, including balance (one-leg stance test), gait and mobility performance (Timed Up and Go, 4-meter walk test), leg muscle strength (5-time sit-to-stand), and estimated cardiorespiratory fitness (Matthews’ questionnaire). Exploratory outcomes include mood, anxiety, and health-related quality of life as assessed by self-reported questionnaires (i.e., Geriatric depression scale-30 items, Perceived stress scale, State-trait anxiety inventory-36 items, Perseverative thinking questionnaire, Connor-Davidson Resilience Scale 10, and 12-item Short Form Survey). This trial will document the remote monitoring of home-based physical exercise alone and home-based physical combined with cognitive training to enhance cognitive and physical health of older adults during the COVID-19 pandemic period. Remote interventions represent a promising strategy to help maintain or enhance health and cognition in seniors, and potentially an opportunity to reach older adults in remote areas, where access to such interventions is limited. Clinical trial Identifier NCT04635462 . COVEPIC was retrospectively registered on November 19, 2020.
机译：在Covid -19大流行，锁定和社会疏散措施的上下文中，以防止病毒的传播。众所周知，监禁和社会隔离可能对身心健康产生负面影响，包括认知。身体活动和认知培训可以帮助提高老年人的认知和身体健康，并防止社会孤立和身体不活动的负面抵押力影响。 CoVepic研究旨在记录6？几个月的家庭体育锻炼的影响与家庭的体育锻炼相结合成年人的认知和身体功能的认知培训。将招募一百二十两名健康老年人（＆ 50？岁）将从社区中招募，并随机到两只武器之一6？几个月：（1）单独的家庭体育锻炼监测和（2）与家庭的认知培训相结合的体育锻炼监测。主要结果是认知，包括一般功能（蒙特利尔认知评估（MOCA）得分），以及执行职能，加工速度和集中内存（基于验证的神经心理学测试和计算机化任务的复合Z分数）。二次结果是物理功能，包括余额（单腿立姿态测试），步态和移动性能（定时和去，4米的步道测试），腿部肌肉力量（5次坐在座位）和估计心肺刺激健身（马修斯的问卷）。探索性结果包括通过自我报告的问卷评估的情绪，焦虑和与健康相关的生活质量（即老年人抑郁症-30项，感知压力规模，状态性焦虑库存-66项，坚持不懈的思维问卷，康纳 - 戴维森弹性量表10，12项短型调查）。该试验将记录单独的家庭物理锻炼的远程监测，以及以家庭为基础的物理相结合，与认知培训，以加强Covid-19大流行期间老年人的认知和身体健康。远程干预措施代表着有希望的策略，以帮助维护或提高老年人的健康和认知，并潜在机会在偏远地区到达偏远地区的老年人有限。临床试验标识符NCT04635462。 Covepic在2020年11月19日回顾性地注册。

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