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Heavy-Ion Microbeams for Biological Science: Development of System and Utilization for Biological Experiments in QST-Takasaki

机译：用于生物科学的重离子微沟：QST-Takasaki生物实验的系统和利用的发展

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Target irradiation of biological material with a heavy-ion microbeam is a useful means to analyze the mechanisms underlying the effects of heavy-ion irradiation on cells and individuals. At QST-Takasaki, there are two heavy-ion microbeam systems, one using beam collimation and the other beam focusing. They are installed on the vertical beam lines of the azimuthally-varying-field cyclotron of the TIARA facility for analyzing heavy-ion radiation effects on biological samples. The collimating heavy-ion microbeam system is used in a wide range of biological research not only in regard to cultured cells but also small individuals, such as silkworms, nematode C. elegans, and medaka fish. The focusing microbeam system was designed and developed to perform more precise target irradiation that cannot be achieved through collimation. This review describes recent updates of the collimating heavy ion microbeam system and the research performed using it. In addition, a brief outline of the focusing microbeam system and current development status is described.
机译：用重离子微观的生物材料的靶辐射是分析重离子照射对细胞和个体效果的机制的有用手段。在QST-Takasaki，有两种重离子Microbeam系统，一个使用梁准直和另一个光束聚焦。它们安装在Tiara设施的间隔变化场回旋加速器的垂直梁线上，用于分析对生物样品的重离子辐射效应。准直的重离子微观系统用于广泛的生物学研究，不仅在培养细胞方面，还用于蚕豆，如家蚕，线虫C.秀丽隐杆线，和Medaka鱼。设计并开发了聚焦微波系统以执行更精确的目标照射，不能通过准直实现。该评论描述了最近的准直离子Microbeam系统更新和使用它进行的研究。此外，还描述了专注的微观系统和电流发展状态的简要概要。

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