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Metastasis of breast cancer to liver through direct lymphatic drainage: a case report

机译:通过直接淋巴排水使乳腺癌转移到肝脏:案例报告

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Breast cancer liver metastasis (BCLM) is considered to occur by hematogenous spread of primary breast cancer cells. We herein present a case of lymphatic BCLM that was confirmed by preoperative imaging for sentinel lymph node biopsy (SLNB). A woman in her early 70s was diagnosed with clinical stage T2N0M0 invasive lobular cancer of the left breast. She underwent mastectomy with SLNB. Preoperative lymphoscintigraphy showed intense accumulation of isotope in the upper abdomen, corresponding to segment IV of the liver on single-photon emission computed tomography/computed tomography (SPECT/CT). However, no abnormalities were detected on magnetic resonance imaging. At 2.5 years postoperatively, the patient’s serum CA15-3 concentration was elevated, and positron emission tomography/computed tomography (PET/CT) showed a solitary liver metastasis. The PET/CT findings were similar to the SPECT/CT findings obtained 2.5 years earlier, indicating that the BCLM had developed lymphatically. To the best of our knowledge, this is the first case report of lymphatic BCLM proven by imaging examination.
机译:乳腺癌肝转移(BCLM)被认为是由原发性乳腺癌细胞的血液发生扩散发生的。我们在本文中提出了一种淋巴化BCLM的情况,通过术前成像对Sentinel淋巴结活检(SLNB)进行了证实。 70岁的女性被诊断出患有左乳房的临床阶段T2N0M0侵袭性小叶癌。她用slnb接受了乳房切除术。术前淋巴管形状显示上腹部中同位素的强烈积累,对应于单光子发射计算机断层扫描/计算断层扫描(SPECT / CT)的肝脏的段IV。然而,在磁共振成像上没有检测到异常。术后2.5岁,患者的血清Ca15-3浓度升高,正电子发射断层扫描/计算机断层扫描(PET / CT)显示出孤立性肝脏转移。 PET / CT发现类似于25年前获得的SPECT / CT结果,表明BCLM已经淋巴地发展淋巴。据我们所知,这是通过成像考试证明的淋巴BCLM的第一个案例报告。

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