Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

M. Schlosser; P. W. Mueller; C. Törn; E. Bonifacio; P. J. Bingley; Participating Laboratories

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Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

机译：糖尿病抗体标准化计划：评估胰岛素自身抗体的检测方法

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Aims/hypothesis Insulin autoantibodies (IAA) are important in type 1 diabetes risk assessment. However, their determination varies more between laboratories than other diabetes autoantibodies. The Diabetes Antibody Standardization Program (DASP) aims to improve and standardise measurement of autoantibodies associated with type 1 diabetes. We report the results of measurement of IAA from DASP workshops in 2002, 2003 and 2005.

机译：目的/假设胰岛素自身抗体（IAA）在1型糖尿病风险评估中很重要。但是，与其他糖尿病自身抗体相比，它们在实验室之间的确定差异更大。糖尿病抗体标准化计划（DASP）旨在改善和标准化与1型糖尿病相关的自身抗体的测量。我们在2002年，2003年和2005年的DASP研讨会上报告了IAA的测量结果。

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《Diabetologia》 |2010年第12期|p.2611-2620|共10页
作者
M. Schlosser; P. W. Mueller; C. Törn; E. Bonifacio; P. J. Bingley; Participating Laboratories;
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正文语种 eng
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关键词
Adjusted sensitivity; AUC; Insulin autoantibodies; Insulin autoantibody index; Islet autoantibodies; Prediction; Reference serum; Sensitivity; Specificity;

机译：调节灵敏度;AUC;胰岛素自身抗体;胰岛素自身抗体指数;胰岛自身抗体;预测;参考血清;灵敏度;特异性;

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1. Diabetes antibody standardization program: first proficiency evaluation of assays for autoantibodies to zinc transporter 8. [J] . Lampasona V, Schlosser M, Mueller PW, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 2011,第12期

机译：糖尿病抗体标准化计划：针对锌转运蛋白8的自身抗体测定的首次能力评估。
2. Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2beta. [J] . Schlosser M, Mueller PW, Achenbach P, Diabetes care . 2011,第11期

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3. Diabetes Antibody Standardization Program: First Proficiency Evaluation of Assays for Autoantibodies to Zinc Transporter 8 [J] . Alistair J.K. Williams, Janet M. Wenzlau, John C. Hutton, Clinical Chemistry: Journal of the American Association for Clinical Chemists . 2011,第12期

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4. Standardization of the assay method for anti-A/B antibody titers and its problems [C] . Takaaki Kobayash Nihon Ishoku Gakkai . 2006

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5. Evaluating Hypoglycemic Risk of Two Basal Insulin Delivery Methods for Type 1 Diabetes: A Comparison of Tresiba Insulin Against Continuous Subcutaneous Insulin Infusion Using Data from Continuous Glucose Monitors [D] . Lane, Benjamin. 2020

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6. Intrinsic insulin secretion capacity might be preserved by discontinuing anti‐programmed cell death protein 1 antibody treatment in ‘anti‐programmed cell death protein 1 antibody‐induced’ fulminant type 1 diabetes [O] . Gota Sakai, Daigo Saito, Ritsuko Nakajima, 2018

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7. Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies [O] . Schlosser, M., Mueller, P. W., Törn, Carina, 2010

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Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

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