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首页> 外文期刊>Digestive Diseases and Sciences >Direct Comparison of Impedance, Manometry, and pH Probe in Detecting Reflux Before and After a Meal
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Direct Comparison of Impedance, Manometry, and pH Probe in Detecting Reflux Before and After a Meal

机译：在进餐前后检测反流的阻抗，测压和pH探头的直接比较

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Combining GERD tests allows strengths and weaknesses of each method to be identified in detecting and characterizing reflux (RE). Aim of this study was to compare two methods that measure bolus volume of a refluxant (impedance monitoring (Imp) and manometry (common cavity)) to pH monitoring which measures changes in acid concentration of a refluxant. Nineteen symptomatic GERD patients and 10 normal volunteers were studied before and after a meal. All had 2-hr simultaneous manometry, pH, and Imp (six sites: 3, 5, 7, 9, 15, 17 cm above LES). Reflux by pH was a fall in pH from above to below 4. There were 973 RE’s in all subjects, but only 19% were detected simultaneously by all three methods. Imp detected more RE’s (96%) than manometry (76%) or pH probe (28%). Imp was the only method to detect 15% (144/973) of RE’s, while detection only by pH probe (2%) or manometry (2%) was rare. Most RE’s detected by Imp were detected simultaneously by manometry (75%,720/937). Those not detected by manometry were usually in blind spots either in the vulnerable period 2–3 sec after a swallow, during a posture change, or during a Valsalva. Most RE’s detected by Imp were not detected by the pH probe. Though most liquid RE’s fasting were detected by pH, most liquid postprandial RE’s were not, due primarily to weakly acidic rather than superimposed acid RE’s. Bolus clearing time by Imp and manometry was nearly identical, while acid clearing was threefold longer than bolus clearing by Imp or manometry. In conclusion, impedance monitoring is better than manometry and pH monitoring in RE detection before and after a meal, and manometry in determining RE composition as liquid or gas. The pH probe measures RE acidity and acid clearing. Simultaneous impedance and pH combines the two methods strengths, and is a powerful tool for reflux detection and characterization.
机译：结合GERD测试，可以在检测和表征回流（RE）时确定每种方法的优缺点。这项研究的目的是比较两种测量回流剂推注体积的方法（阻抗监测（Imp）和测压法（公共腔））与测量pH值以测量回流酸浓度变化的方法。在饭前和饭后对19名有症状的GERD患者和10名正常志愿者进行了研究。全部具有2小时同时测压，pH和Imp（六个部位：位于LES上方3、5、7、9、15、17厘米）。 pH反流是pH值从4下降到4以下。所有受试者中都存在973 RE，但是这三种方法同时检测到19％。 Imp检出的RE（96％）比测压法（76％）或pH探针（28％）多。 Imp是检测15％（144/973）RE的唯一方法，而仅通过pH探针（2％）或测压法（2％）进行检测的方法很少。 Imp检测到的大多数RE都是通过测压法同时检测到的（75％，720/937）。测压法未检测到的那些人通常在吞咽后2-3秒的脆弱时期，姿势改变期间或瓦尔萨尔瓦时期处于盲点。 pH探针无法检测到Imp所检测到的大多数RE。尽管大多数液态RE的禁食都是通过pH值检测的，但大多数液态餐后RE却没有，主要是由于弱酸性，而不是叠加酸性RE。 Imp和测压法清除小块的时间几乎相同，而酸清除比Imp测压或测压的大剂量清除长三倍。总之，在饭前和饭后进行RE检测以及在确定RE成分为液体或气体时，阻抗监测优于压力监测和pH监测。 pH探针可测量RE酸度和酸清除率。同时的阻抗和pH值结合了这两种方法的优势，是回流检测和表征的强大工具。

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