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Acid Perfusion Test: A Useful Test for Evaluating Esophageal Acid Sensitivity

机译:酸灌注试验:评估食管酸敏感性的有用试验

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摘要

The acid perfusion test (APT) is a test of esophageal acid sensitivity. In gastroesophageal reflux disease (GERD), the APT has largely been superseded by indexes derived from 24-hr esophageal pH monitoring: symptom index (SI), symptom sensitivity index (SSI), and symptom association probability (SAP). To evaluate the role of APT in patients with GERD we compared values of SI, SSI, and SAP in 126 APT+ and 146 APT− patients. Median values for SI, SSI, and SAP were higher in the APT+ compared with the APT− group (P < 0.001). More patients had a positive SI, SSI, and SAP in the APT+ compared with the APT– group (SI, P < 0.0001; SSI and SAP, P < 0.001). Patients with a negative APT were unlikely to have symptoms caused by acid reflux (negative predictive value, 86%). APT may be useful in detecting acid sensitivity in patients who do not report symptoms on 24-hr esophageal pH monitoring.
机译:酸灌注测试(APT)是对食道酸敏感性的测试。在胃食管反流疾病(GERD)中,APT已被24小时食管pH监测得出的指标所取代:症状指数(SI),症状敏感性指数(SSI)和症状关联概率(SAP)。为了评估APT在GERD患者中的作用,我们比较了126名APT +和146名APT-患者的SI,SSI和SAP值。与APT-组相比,APT +中SI,SSI和SAP的中位数值更高(P <0.001)。与APT–组相比,APT +组中SI,SSI和SAP阳性的患者更多(SI,P <0.0001; SSI和SAP,P <0.001)。 APT阴性的患者不太可能出现由反酸引起的症状(阴性预测值86%)。对于在24小时食管pH监测中未报告症状的患者,APT可用于检测酸敏感性。

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