Ezetimibe - a new cholesterol-lowering drug

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Ezetimibe - a new cholesterol-lowering drug

机译：Ezetimibe-一种新的降低胆固醇的药物

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Use of statin therapy is a key first-line approach in preventing coronary heart disease events and stroke in people at increased risk of developing such complications. TEzetimibe (Ezetrol - MSD-Schering-Plough), the first licensed azetidinone drug, is being promoted as an adjunct to statin therapy to achieve greater reductions in blood cholesterol concentrations than occur with a statin alone. Here we review ezetimibe and consider its place in clinical practice.

机译：他汀类药物的使用是预防冠心病事件和中风的关键一线方法，这些人发生此类并发症的风险增加。 TEzetimibe（Ezetrol-MSD-Schering-Plough），第一种获得许可的氮杂环丁酮药物，正在被推荐作为他汀类药物疗法的辅助手段，以实现比单独使用他汀类药物更大的血胆固醇浓度降低。在这里，我们回顾了依折麦布并考虑其在临床实践中的地位。

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《Drug and Therapeutics Bulletin》 |2004年第9期|p.65-67|共3页
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收录信息美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类药学;
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1. Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer [J] . BoKobber? Lauridsen, StefanStender, RuthFrikke-Schmidt, International Journal of Epidemiology: Official Journal of the International Epidemiological Association . 2017,第6期

机译：使用遗传学探索胆固醇降低药物ezetimibe可能导致癌症的风险增加
2. Quantitative Analysis of the Cholesterol-Lowering Drugs Ezetimibe and Simvastatin in Pure Powder, Binary Mixtures, and a Combined Dosage Form by Spectrophotometry, Chemometry, and High-Performance Column Liquid Chromatography [J] . Lotfy Hayam Mahmoud, Alamein Amal Mahmoud Aboul, Hegazy Maha Abdel Monem . Journal of AOAC International . 2010,第6期

机译：分光光度法，化学计量学和高效液相色谱法定量分析纯粉末，二元混合物和混合剂型中的降胆固醇药物依泽替米贝和辛伐他汀
3. Evaluating the safety of Liptruzet (ezetimibe and atorvastatin): what are the potential benefits beyond low-density lipoprotein cholesterol-lowering effect? [J] . Husain Nazik Elmalaika, Hassan Abdallah Tang, Elmadhoun Wadie M., Expert opinion on drug safety . 2015,第9期

机译：评估Liptruzet（依泽替米贝和阿托伐他汀）的安全性：除了降低低密度脂蛋白胆固醇的作用外，还有哪些潜在益处？
4. Disappointing Recent Cholesterol-Lowering Drug Trials: Is It Not Time for a Full Reappraisal of the Cholesterol Theory? [C] . Michel de Lorgeril Congress of the International Society of Nutrigenetic/Nutrigenomics . 2009

机译：令人失望的最近胆固醇降低的药物试验：它不是胆固醇理论的全部重新获得的时间吗？
5. Ileal bile acid transporter inhibitors: A search for new, alternative cholesterol-lowering drugs using methods in pharmacology and information science. [D] . Root, Carolyn. 2005

机译：回肠胆汁酸转运蛋白抑制剂：使用药理学和信息科学方法寻找新的替代性降胆固醇药物。
6. Influence of Previous Statin Therapy on Cholesterol-Lowering Effect of Ezetimibe [O] . Young Hwan Choi, Young Kim, Cheol Won Hyeon, 2014

机译：以前的他汀类药物治疗对依泽替米贝降低胆固醇的影响
7. Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer [O] . Bo Kobberø Lauridsen, Stefan Stender, Ruth Frikke-Schmidt, 2017

机译：使用遗传学探索胆固醇降低药物ezetimibe可能导致癌症的风险增加

Ezetimibe - a new cholesterol-lowering drug

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