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Characterizing particulate drug-delivery carriers with atomic force microscopy

机译:用原子力显微镜表征颗粒状药物递送载体

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This work discusses the benefits of employing an atomic force microscope (AFM) in the characterization of the particulate-type drug-delivery carriers. AFM can provide invaluable information about the physicochemical characteristics of the carriers that play an important role in determining the performance of the drug delivery systems (DDS). A lot of this information cannot be obtained from other characterization techniques due to the unique ability of the AFM to probe nanometer scale features at the molecular level. There has already been a significant amount of work in the development of the DDS and the upcoming of AFM as a powerful characterizing tool provides a new inspiration in this area. This will definitely add to the understanding of the DDS and will influence the future designs of the drug carriers towards the development of better and more efficient DDS.
机译:这项工作讨论了使用原子力显微镜(AFM)表征颗粒型药物递送载体的好处。 AFM可以提供有关载体的理化特性的宝贵信息,这些信息在决定药物递送系统(DDS)的性能中起着重要作用。由于AFM能够在分子水平上探测纳米级特征,因此无法从其他表征技术中获得很多此类信息。在DDS的开发中已经进行了大量的工作,而即将到来的AFM作为一种强大的表征工具在这一领域提供了新的灵感。这肯定会增加对DDS的理解,并会影响药物载体的未来设计,以开发更好,更高效的DDS。

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