...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Talanta: The International Journal of Pure and Applied Analytical Chemistry >Application of atomic force microscopy to characterize liposomes as drug and gene carriers
【24h】

Application of atomic force microscopy to characterize liposomes as drug and gene carriers

机译：应用原子力显微镜将脂质体表征为药物和基因载体

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

At present,liposomes play a significant role as drug delivery vehicles being considered very promising for gene therapeutics.The in vivo application of these drug delivery systems widely depends on their physico-chemical and technological characteristics such as the structure,the shape,the size distribution,the surface modification and the drug interaction.To describe the liposomes,different analytical techniques were used.In this paper,we reviewed the application of the atomic force microscopy(AFM),one of the most commonly applied scanning probe microscopy(SPM)techniques,in the description of liposome.The advantages and limitations of these techniques are discussed comparing the reported data with those referred to other well-know microscopical and spectroscopical techniques such as transmission electron microscopy(TEM)and photon correlation spectroscopy(PCS).A detailed description of the application of AFM to evaluate the formation and the geometry of liposomes/DNA complexes is presented.
机译：目前，脂质体作为药物输送载体在基因治疗中被认为是非常有前途的。这些药物输送系统的体内应用在很大程度上取决于其理化和技术特征，例如结构，形状，大小分布。为了描述脂质体，使用了不同的分析技术。本文综述了原子力显微镜（AFM）的应用，原子力显微镜是最常用的扫描探针显微镜（SPM）技术之一。通过比较所报告的数据与其他众所周知的显微和光谱技术，例如透射电子显微镜（TEM）和光子相关光谱（PCS），讨论了这些技术的优点和局限性。详细原子力显微镜用于评估脂质体/ DNA复合物的形成和几何形状的应用的描述恩特

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号