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首页> 外文期刊>Environmental Pollution >Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)
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Genotoxicity biomarkers and acetylcholinesterase activity in natural populations of Mytilus galloprovincialis along a pollution gradient in the Gulf of Oristano (Sardinia, western Mediterranean)

机译：沿污染梯度在奥里斯塔诺湾（撒丁岛，地中海西部）的米氏us自然种群中的自然毒性的遗传毒性生物标志物和乙酰胆碱酯酶活性

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摘要

A year-round biomonitoring study on blue mussels (Mytilus galloprovincialis) was carried out in 4 selected sites along the Gulf of Oristano (Sardinia, Italy): a commercial port (Port), the outlet of the S'Ena Arrubia and Marceddi lagoons (in the catchment area of intensive agricultural and diary activities, and abandoned mining), and a reference site (North). Heavy metal concentrations in sediments from Marceddi were 2—3 to 10—20 times higher in Pb, Cd and Zn, respectively, than those found at North and S'Ena Arrubia. Higher values (P < 0.05) of micronuclei frequency were detected in mussels from Marceddi and Port compared to those detected in mussels from North and S'Ena Arrubia. DNA damage in animals from North was significantly lower than that at the other sites. Results of acetylcholinesterase inhibition consistently showed the strongest effects in mussels from Port and Marceddi. Our results suggest that these biomarkers can be used in coastal marine biomonitoring as early signals of exposure and adverse effects along a pollution gradient.
机译：在奥里斯塔诺湾（意大利撒丁岛）的四个选定地点进行了蓝贻贝（Mytilus galloprovincialis）的全年生物监测研究：商业港口（Port），S'Ena Arrubia出口和Marceddi泻湖（在集约化农业和日记活动以及废弃采矿的集水区）和参考地点（北部）。 Marceddi沉积物中重金属的铅，镉和锌含量分别比北部和塞纳阿鲁比亚高2–3至10-20倍。在Marceddi和Port的贻贝中检测到的微核频率值高于在North和S'Ena Arrubia中的贻贝中检测到的值（P <0.05）。来自北方的动物的DNA损伤明显低于其他部位。乙酰胆碱酯酶抑制作用的结果始终显示，来自Port和Marceddi的贻贝的效果最强。我们的结果表明，这些生物标记物可用于沿海海洋生物监测，作为沿污染梯度的暴露和不利影响的早期信号。

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