• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Pollution >Environmental risk assessment of triclosan and ibuprofen in marine sediments using individual and sub-individual endpoints
【24h】

Environmental risk assessment of triclosan and ibuprofen in marine sediments using individual and sub-individual endpoints

机译：使用个体和亚个体终点评估海洋沉积物中三氯生和布洛芬的环境风险

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The guidelines for the Environmental Risk Assessment (ERA) of pharmaceuticals and personal care products (PPCP) recommend the use of standard ecotoxicity assays and the assessment of endpoints at the individual level to evaluate potential effects of PPCP on biota. However, effects at the sub-individual level can also affect the ecological fitness of marine organisms chronically exposed to PPCP. The aim of the current study was to evaluate the environmental risk of two PPCP in marine sediments: triclosan (TCS) and ibuprofen (IBU), using sub-individual and developmental endpoints. The environmental levels of TCS and IBU were quantified in marine sediments from the vicinities of the Santos submarine sewage outfall (Santos Bay, Sao Paulo, Brazil) at 15.14 and 49.0 ng g(-1), respectively. A battery (n = 3) of chronic bioassays (embryo-larval development) with a sea urchin (Lytechinus variegatus) and a bivalve (Perna perna) were performed using two exposure conditions: sediment-water interface and elutriates. Moreover, physiological stress through the Neutral Red Retention Time Assay (NRRT) was assessed in the estuarine bivalve Mytella charruana exposed to TCS and IBU spiked sediments. These compounds affected the development of L. variegatus and P. perna (75 ng g(-1) for TCS and 15 ng g(-1) for IBU), and caused a significant decrease in M. charruana lysosomal membrane stability at environmentally relevant concentrations (0.08 ng g(-1) for TCS and 0.15 ng g(-1) for IBU). Chemical and ecotoxicological data were integrated and the risk quotient estimated for TCS and IBU were higher than 1.0, indicating a high environmental risk of these compounds in sediments. These are the first data of sediment risk assessment of pharmaceuticals and personal care products of Latin America. In addition, the results suggest that the ERA based only on individual-level and standard toxicity tests may overlook other biological effects that can affect the health of marine organisms exposed to PPCP. (C) 2017 Elsevier Ltd. All rights reserved.
机译：药品和个人护理产品（PPCP）的环境风险评估（ERA）指南建议使用标准的生态毒性测定法以及对个体水平的终点进行评估，以评估PPCP对生物群的潜在影响。但是，亚个体水平的影响也可能影响长期暴露于PPCP的海洋生物的生态适应性。本研究的目的是使用亚个体和发育终点来评估海洋沉积物中两种PPCP的环境风险：三氯生（TCS）和布洛芬（IBU）。在来自桑托斯海底污水排放口（巴西圣保罗的桑托斯湾）附近的海洋沉积物中，TCS和IBU的环境水平分别为15.14 ng g（-1）和49.0 ng g（-1）。在两个暴露条件下进行了一系列电池（n = 3）的慢性生物测定（胚胎幼虫发育）和海胆（Lytechinus variegatus）和双壳类（Perna perna）：沉积物-水界面和洗出液。此外，通过暴露于TCS和IBU加标沉积物中的河口双壳类Mytella charruana评估了通过中性红色保留时间测定（NRRT）引起的生理压力。这些化合物影响了L.variegatus和P.perna的发育（对于TCS为75 ng g（-1），对于IBU为15 ng g（-1）），并在与环境相关的环境中导致了Charruana溶酶体膜稳定性的显着降低。浓度（TCS为0.08 ng g（-1），IBU为0.15 ng g（-1））。综合化学和生态毒理学数据，TCS和IBU的风险商估计高于1.0，表明这些化合物在沉积物中的环境风险很高。这些是拉丁美洲药品和个人护理产品沉积物风险评估的第一笔数据。此外，结果表明，仅基于个体水平和标准毒性测试的ERA可能忽略了其他可能影响暴露于PPCP的海洋生物健康的生物学效应。 （C）2017 Elsevier Ltd.保留所有权利。

著录项

  • 来源
    《Environmental Pollution》 |2018年第1期|274-283|共10页
  • 作者

    Pusceddu F. H.; Choueri R. B.; Pereira C. D. S.; Cortez F. S.; Santos D. R. A.; Moreno B. B.; Santos A. R.; Rogero J. R.; Cesar A.;

  • 作者单位

    Univ Sao Paulo, Inst Pesquisas Energet & Nucl, Ctr Quim & Meio Ambiente, Sao Paulo, SP, Brazil|Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil;

    Univ Fed Sao Paulo, Dept Ciencias Mar, Campus Baixada Santista, Santos, SP, Brazil;

    Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil|Univ Fed Sao Paulo, Dept Ciencias Mar, Campus Baixada Santista, Santos, SP, Brazil;

    Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil;

    Univ Sao Paulo, Inst Pesquisas Energet & Nucl, Ctr Quim & Meio Ambiente, Sao Paulo, SP, Brazil;

    Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil;

    Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil;

    Univ Sao Paulo, Inst Pesquisas Energet & Nucl, Ctr Quim & Meio Ambiente, Sao Paulo, SP, Brazil;

    Univ Santa Cecilia, Lab Ecotoxicol, Santos, SP, Brazil|Univ Fed Sao Paulo, Dept Ciencias Mar, Campus Baixada Santista, Santos, SP, Brazil;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Environmental risk assessment; Pharmaceuticals and personal care products; Mytella charruana; Lytechinus variegatus; Perna perna;

    机译：环境风险评估;药品和个人护理产品;链霉菌（Mytella charruana）;百日草（Lytechinus variegatus）;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号