Bisphenol-A in breast adipose tissue of breast cancer cases and controls

Reeves Katherine W.; Schneider Sallie; Xue Jingchuan; Kannan Kurunthachalam; Mason Holly; Johnson Melissa; Makari-Judson Grace; Santana Mary Diaz

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Bisphenol-A in breast adipose tissue of breast cancer cases and controls

机译：乳腺癌乳腺组织中双酚A的情况及对策

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We evaluated whether bisphenol-A (BPA) could be quantified in breast adipose tissue samples provided by 36 breast cancer mastectomy patients and 14 reduction mammoplasty patients. Samples of breast adipose tissue were collected and BPA concentration was quantified using HPLC-ESI-MS/MS. BPA was detectable above the limit of quantitation of 0.38 ng/g in 30.6% of samples. BPA concentrations varied within- and between breasts and were similar between cases and controls (0.39 vs 0.41 ng/g, p = 0.74).

机译：我们评估了双酚A（BPA）是否可以在由36例乳腺癌乳腺切除术患者和14例复位乳腺成形术患者提供的乳腺脂肪组织样品中进行定量。收集乳房脂肪组织样品，并使用HPLC-ESI-MS / MS对BPA浓度进行定量。在30.6％的样品中，可检测到的BPA超过0.38 ng / g的定量限。乳房内和乳房之间的BPA浓度各不相同，病例与对照之间的BPA浓度相似（0.39 vs 0.41 ng / g，p = 0.74）。

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来源
《Environmental research》 |2018年第11期|735-738|共4页
作者
Reeves Katherine W.; Schneider Sallie; Xue Jingchuan; Kannan Kurunthachalam; Mason Holly; Johnson Melissa; Makari-Judson Grace; Santana Mary Diaz;
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作者单位

Univ Massachusetts, Dept Biostat & Epidemiol, 715 North Pleasant St, Amherst, MA 01003 USA;

Baystate Hlth, Pioneer Valley Life Sci Inst, 3601 Main St, Springfield, MA USA;

SUNY Albany, Sch Publ Hlth, New York State Dept Hlth, Wadsworth Ctr, 120 New Scotland Ave, Albany, NY 12222 USA;

SUNY Albany, Sch Publ Hlth, New York State Dept Hlth, Wadsworth Ctr, 120 New Scotland Ave, Albany, NY 12222 USA;

Baystate Hlth, Dept Surg, 759 Chestnut St, Springfield, MA USA;

Pioneer Valley Plast Surg, 100 Wesson Ave 360, Springfield, MA USA;

Baystate Reg Canc Program, 3350 Main St, Springfield, MA USA;

Univ Massachusetts, Dept Biostat & Epidemiol, 715 North Pleasant St, Amherst, MA 01003 USA;

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原文格式 PDF
正文语种 eng
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关键词
Bisphenol-A; Breast; Cancer; Adipose; Endocrine disruption;

机译：双酚A;乳腺癌;癌症;脂肪;内分泌干扰;

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Bisphenol-A in breast adipose tissue of breast cancer cases and controls

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