...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental research >A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements
【24h】

A systematic review of associations between maternal exposures during pregnancy other than smoking and antenatal fetal measurements

机译：对孕妇除吸烟和产前胎儿测量外的暴露之间的关联进行系统的回顾

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Reduced birth weight is associated with many maternal environmental exposures during pregnancy, but the gestational age at onset of this association is unknown. We have previously reported associations between maternal smoking and fetal size.Objective: To report on our systematic review of the literature describing associations between antenatal size and growth and maternal exposures during pregnancy.Data sources: Electronic databases (OVID and EMBASE) and web sites for cohort studies were searched. Studies were eligible if they examined associations between maternal environmental exposures (including ambient air exposure, diet and alcohol) and antenatal fetal ultrasound measurements. The Navigation Guide was used to assess the strength of evidence.Results: There were 451 abstracts identified and 36 papers were included of which maternal diet was the exposure of interest in 15, maternal ambient air exposure in 10, maternal alcohol in 3 and other exposures in 8. The first paper was published in 2006. Associations were present between exposures and fetal measurements in 18% of comparisons with second trimester measurements and in 46% of comparisons with third trimester measurements. In the third trimester, when an association was present, reduced head size was most commonly (58%) associated with current or previous maternal exposure, with reduced length being least commonly (32%) associated and reduced weight being intermediate (52%). In the third trimester, increased maternal nitrogen dioxide exposure was associated with reduced head size was associated with in all seven studies identified and reduced fetal weight in five out of six studies.Conclusion: There is sufficient evidence of toxicity in the context of maternal exposure to nitrogen dioxide and reduced third trimester fetal head size. There is currently insufficient evidence of toxicity with regard to maternal exposures to dietary factors, alcohol and environmental chemicals and reduced fetal size.
机译：背景：出生时体重减轻与怀孕期间许多母亲的环境暴露有关，但是这种关联的开始时的胎龄尚不清楚。我们以前曾报道过孕妇吸烟与胎儿大小之间的关联。目的：报告我们对描述产前胎儿大小和成长与怀孕期间母亲暴露之间关联的文献的系统综述。数据来源：电子数据库（OVID和EMBASE）和网站队列研究进行了搜索。如果研究检查了母亲的环境暴露（包括环境空气暴露，饮食和酒精）与产前胎儿超声测量之间的关联，则这些研究是合格的。结果：共鉴定了451篇摘要，包括36篇论文，其中，母体饮食是关注的暴露者15，母体空气暴露在10中，母体酒精在3种中以及其他暴露[8]在2006年发表的第一篇论文中。暴露和胎儿测量之间存在关联，其中18％的妊娠中期测量结果和46％的妊娠晚期测量结果之间存在关联。在妊娠中期，当存在关联时，头部尺寸减小最常见（58％）与当前或先前的母体暴露相关，长度减小最不常见（32％）与体重减轻之间（52％）。在孕晚期，在所有七项确定的研究中，孕妇暴露于二氧化氮的增加与头部大小的减少有关，而六项研究中的五项则与胎儿体重的减少有关。结论：有足够的证据表明，孕妇暴露于二氧化氮中会产生毒性。二氧化氮和孕晚期胎儿头的大小减少。目前，没有足够的证据表明母亲对饮食因素，酒精和环境化学物质的接触以及胎儿大小的减少具有毒性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号