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A panel study of the acute effects of personal exposure to household air pollution on ambulatory blood pressure in rural Indian women

机译:关于印度农村妇女个人暴露于家庭空气污染对动态血压的急性影响的专题研究

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摘要

Background: Almost half the world's population is exposed to household air pollution from biomass and coal combustion. The acute effects of household air pollution on the cardiovascular system are poorly characterized. We conducted a panel study of rural Indian women to assess whether personal exposures to black carbon during cooking were associated with acute changes in blood pressure. Methods: We enrolled 45 women (ages 25-66 years) who cooked with biomass fuels. During cooking sessions in winter and summer, we simultaneously measured their personal real-time exposure to black carbon and conducted ambulatory blood pressure measurements every 10 min. We recorded ambient temperature and participants' activities while cooking. We assessed body mass index, socioeconomic status, and salt intake. Multivariate mixed effects regression models with random intercepts were used to estimate the associations between blood pressure and black carbon exposure, e.g., average exposure in the minutes preceding blood pressure measurement, and average exposure over an entire cooking session. Results: Women's geometric mean (GM) exposure to black carbon during cooking sessions was lower in winter (GM: 40 μg/m~3; 95% CI: 30, 53) than in summer (GM: 56 |ig/m~3; 95% Cl: 42, 76). Interquartile range increases in black carbon were associated with changes in systolic blood pressure from -0.4 mm Hg (95% CI: -2.3, 1.5) to 1.9 mm Hg (95% CI: -0.8, 4.7), with associations increasing in magnitude as black carbon values were assessed over greater time periods preceding blood pressure measurement. Interquartile range increases in black carbon were associated with small decreases in diastolic blood pressure from -0.9 mm Hg (95% CI: -1.7, -0.1)to -0.4 mm Hg (95% CI: -1.6, 0.8). Associations of a similar magnitude were estimated for cooking session-averaged values. Conclusions: We found some evidence of an association between exposure to black carbon and acute increases in systolic blood pressure in Indian women cooking with biomass fuels, which may have implications for the development of cardiovascular diseases.
机译:背景:世界上将近一半的人口暴露于由生物质和煤炭燃烧引起的家庭空气污染。家庭空气污染对心血管系统的急性影响尚不明确。我们对印度农村妇女进行了一项小组研究,以评估在烹饪过程中个人接触黑碳是否与血压的急剧变化有关。方法:我们招募了45位年龄在25-66岁之间的以生物质燃料做饭的妇女。在冬季和夏季的烹饪过程中,我们同时测量了他们个人对黑碳的实时暴露量,并每10分钟进行一次动态血压测量。我们记录了烹饪时的环境温度和参与者的活动。我们评估了体重指数,社会经济状况和食盐摄入量。具有随机截距的多元混合效应回归模型用于估算血压与黑碳暴露之间的关联,例如血压测量前几分钟的平均暴露量以及整个烹饪过程中的平均暴露量。结果:冬季(GM:40μg/ m〜3; 95%CI:30、53)与冬季(GM:56 | ig / m〜3)相比,女性在烹饪过程中接触黑碳的几何平均值(GM)更低; 95%Cl:42、76)。黑碳四分位数间距的增加与收缩压从-0.4 mm Hg(95%CI:-2.3,1.5)到1.9 mm Hg(95%CI:-0.8,4.7)的变化有关,并且随着幅度的增加而增加在血压测量之前的较长时间内评估了黑碳值。黑碳的四分位数间距增加与舒张压从-0.9 mm Hg(95%CI:-1.7,-0.1)到-0.4 mm Hg(95%CI:-1.6,0.8)的小幅降低相关。估计烹饪会议的平均值具有相似大小的关联。结论:我们发现一些证据表明,在使用生物质燃料烹饪的印度妇女中,接触黑碳与收缩压急剧升高之间存在关联,这可能对心血管疾病的发展有影响。

著录项

  • 来源
    《Environmental research》 |2016年第5期|331-342|共12页
  • 作者单位

    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada;

    Department of Medicine, McGill University, Montreal, QC, Canada,Division of Clinical Epidemiology, Research Institute, McGill University Health Centre, Montreal, QC, Canada;

    Department of Civil, Environmental, and Geo-Engineering, University of Minnesota, Minneapolis, MN, USA;

    Department of Medicine, McGill University, Montreal, QC, Canada,Division of Clinical Epidemiology, Research Institute, McGill University Health Centre, Montreal, QC, Canada;

    SAMUHA, Kanakagiri, Karnataka, India;

    SAMUHA, Kanakagiri, Karnataka, India;

    SAMUHA, Kanakagiri, Karnataka, India;

    SAMUHA, Kanakagiri, Karnataka, India;

    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada,Institute for Health and Social Policy, McGill University, Montreal, QC, Canada,Institute for Health and Social Policy, McGill University, 1130 Pine Avenue West Montreal, Quebec, Canada H3A 1A3;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Biomass combustion; Black carbon; Cardiovascular; Acute effects; Panel study;

    机译:生物质燃烧黑炭;心血管;急性影响;专题研究;

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