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Short-term exposure to noise, fine particulate matter and nitrogen oxides on ambulatory blood pressure: A repeated-measure study

机译:动态血压对噪声,细颗粒物和氮氧化物的短期暴露:一项重复测量研究

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摘要

Exposure to road traffic noise, fine particulate matter (aerodynamic diameter ≤ 2.5 μm; PM_(2.5)) and nitrogen oxides (NO_x) has been associated with transient changes in blood pressure, but whether an interaction exists remains unclear. This panel study investigated whether noise, PM_(2.5) and NO_x exposure were independently associated with changes in 24-h ambulatory blood pressure. We recruited 33 males and 33 females aged 18-32 years as study subjects. Personal noise exposure and ambulatory blood pressure were monitored simultaneously in 2007. During the data collection periods, 24-h data on PM_(2.5) and NO_x from five air-quality monitors within 6 km of participants' home addresses were used to estimate their individual exposures. Linear mixed-effects regression models were used to estimate single and combined effects on ambulatory blood pressure. Exposure to both noise and PM_(2.5) was significantly associated with increased systolic blood pressure (SBP) and diastolic blood pressure (DBP) over 24 h; NO_x exposure was only significantly related to elevated DBP. Twenty-four-hour ambulatory blood pressure increased with the current noise exposure of 5 A-weighted decibels (dBA) (SBP 1.44 [95% confidence interval: 1.16, 1.71] mmHg and DBP 1.40 [1.18, 1.61] mmHg) and PM_(2.5) exposure of 10-μg/m~3 (SBP 0.81 [0.19, 1.43] mmHg and DBP 0.63 [0.17, 1.10] mmHg), as well as the current NO_x exposure of 10-ppb (DBP 0.54 [0.12, 0.97] mmHg) after simultaneous adjustment. These findings suggest that exposure to noise and air pollutants may independently increase ambulatory blood pressure and the risk of cardiovascular diseases.
机译:暴露于道路交通噪声,细颗粒物(空气动力学直径≤2.5μm; PM_(2.5))和氮氧化物(NO_x)与血压的瞬时变化有关,但尚不清楚是否存在相互作用。该小组研究调查了噪音,PM_(2.5)和NO_x暴露是否与24小时动态血压的变化独立相关。我们招募了年龄在18-32岁之间的33位男性和33位女性作为研究对象。 2007年同时监测了个人噪声暴露和动态血压。在数据收集期间,使用了来自参与者住所6公里内五台空气质量监测仪的PM_(2.5)和NO_x的24小时数据来估算其个人曝光。线性混合效应回归模型用于估计动态血压的单一和联合影响。暴露于噪声和PM_(2.5)与在24小时内收缩压(SBP)和舒张压(DBP)升高显着相关。 NO_x暴露仅与DBP升高显着相关。当前暴露于5 A加权分贝(dBA)(SBP 1.44 [95%置信区间:1.16,1.71] mmHg和DBP 1.40 [1.18,1.61] mmHg)和PM_(24小时动态血压)增加2.5)暴露于10μg/ m〜3(SBP 0.81 [0.19,1.43] mmHg和DBP 0.63 [0.17,1.10] mmHg),以及当前的NO_x暴露10-ppb(DBP 0.54 [0.12,0.97]同时调整后)。这些发现表明,暴露于噪音和空气污染物可能会独立增加动态血压和心血管疾病的风险。

著录项

  • 来源
    《Environmental research》 |2015年第7期|634-640|共7页
  • 作者单位

    Department of Environmental Engineering and Science, Feng Chia University, Taichung, Taiwan;

    Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan,School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan;

    Department of Occupational Safety and Health, College of Public Health, China Medical University, Taichung, Taiwan;

    Department of Occupational Safety and Health, College of Public Health, China Medical University, Taichung, Taiwan;

    School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan,Division of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan;

    Department of Pharmacy, College of Pharmacy, China Medical University, Taichung, Taiwan;

    Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan;

    Department of Occupational Safety and Health, College of Public Health, China Medical University, 91 Hsueh-Shih Road, Taichung 40402, Taiwan, R.O.C.;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Blood pressure; Fine particle; Hypertension; Nitrogen oxides; Noise;

    机译:血压;细颗粒;高血压;氮氧化物;噪声;

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