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首页> 外文期刊>Environmental research >Mortality after exposure to polychlorinated biphenyls and dibenzofurans: 30 years after the 'Yucheng Accident'
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Mortality after exposure to polychlorinated biphenyls and dibenzofurans: 30 years after the 'Yucheng Accident'

机译：暴露于多氯联苯和二苯并呋喃后的死亡率：“禹城事故”发生三十年后

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摘要

Background: In 1979, approximately 2,000 people in central Taiwan were accidentally exposed to polychlorinated biphenyls and dibenzofurans due to ingestion of contaminated cooking oil. This event was called Yucheng, "oil-syndrome" in Chinese. We followed the exposed persons and compared their cause-specific mortality with that of neighborhood referents 30 years after the accident. Methods: We obtained age- and gender-matched referents from the 1979 neighborhoods of the exposed people. Cause-specific mortality was compared between exposed subjects (N=1803) and their neighborhood referents (N=5170) using standardized mortality ratios (SMR). Total person-years for the Yucheng subjects and neighborhood referents were 48,751 and 141,774, respectively. Results: The SMR for all causes (SMR=1.2, 95% CI: 1.1-1.3), diseases of the circulatory system (SMR=1.3, 95% CI: 1.0-1.6), and diseases of the musculoskeletal system and connective tissue (SMR=6.4, 95% CI: 2.8-12.7) were elevated in Yucheng subjects. Among Yucheng males, the SMRs for diseases of the digestive system (SMR=1.9, 95% CI: 1.2-2.8), malignant neoplasm of stomach (SMR=3.5, 95% CI: 1.5-7.0), and malignant neoplasm of lymphatic and hematopoietic tissue (SMR=3.0, 95% CI: 1.1-6.6) were increased. The SMR for total neoplasms was increased (SMR=1.3, 95% CI: 0.9-1.7). Conclusion: We conclude that exposure to PCBs/PCDFs at levels that produced symptoms in many affects mortality patterns 3 decades after exposure.
机译：背景：1979年，台湾中部大约2,000人由于摄入被污染的食用油而意外接触了多氯联苯和二苯并呋喃。这个事件被称为禹城，中文为“石油综合症”。我们追踪了暴露者，并比较了事故发生30年后，其特定原因的死亡率与邻里相关人员的死亡率。方法：我们从暴露人群的1979个社区中获得了年龄和性别相匹配的对象。使用标准化死亡率（SMR），比较了暴露受试者（N = 1803）和他们的邻近对象（N = 5170）的病因特异性死亡率。于城受试者和邻里参照物的总人年分别为48,751和141,774。结果：所有原因的SMR（SMR = 1.2，95％CI：1.1-1.3），循环系统疾病（SMR = 1.3，95％CI：1.0-1.6）以及肌肉骨骼系统和结缔组织疾病（在禹城受试者中SMR = 6.4，95％CI：2.8-12.7）升高。在禹城县男性中，消化系统疾病的SMR（SMR = 1.9，95％CI：1.2-2.8），胃恶性肿瘤（SMR = 3.5，95％CI：1.5-7.0）以及淋巴癌和恶性肿瘤。造血组织（SMR = 3.0，95％CI：1.1-6.6）增加。总肿瘤的SMR增加（SMR = 1.3，95％CI：0.9-1.7）。结论：我们得出的结论是，暴露于PCBs / PCDFs的水平在许多情况下会产生症状，这会影响暴露后3年的死亡率。

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  • 来源
    《Environmental research》 |2013年第1期|71-75|共5页
  • 作者

    Ming-Chieh Li; Pei-Chien Tsai; Pau-Chung Chen; Chia-Jung Hsieh; Yue-Liang Leon Guo; Walter J. Rogan;

  • 作者单位

    Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taiwan;

    Department of Medical Research, Kaohsiung Medical University Hospital, Taiwan;

    Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taiwan;

    Institute of Occupational Medicine and Industrial Hygiene, National Taiwan University College of Public Health, Taiwan;

    Department of Environmental and Occupational Medicine, National Taiwan University College of Medicine, Taiwan,No.l, Section 1, Ren-ai Rd., Zhongzheng Dist., Taipei City 100, Taiwan;

    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, USA;

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  • 正文语种 eng
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  • 关键词

    yucheng; dioxin; polychlorinated biphenyls; polychlorinated dibenzofurans; standardized mortality ratio;

    机译：禹城二恶英多氯联苯;多氯二苯并呋喃;标准化死亡率;

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