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首页> 外文期刊>Environmental research >Association of low-level blood lead and blood pressure in NHANES 1999-2006
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Association of low-level blood lead and blood pressure in NHANES 1999-2006

机译：1999-2006年NHANES中低血铅和血压的协会

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摘要

This study investigated whether low blood-lead levels (≤10μg/dL) were associated with blood pressure (BP) outcomes. The authors analyzed data from National Health and Nutrition Examination Survey 1999-2006 and participants aged 20 years or older. Outcome variables were systolic and diastolic BP measurements, pulse pressure, and hypertension status. Multivariable linear and logistic regressions stratified by race/ethnicity and gender were performed. Blood lead levels (BLL) were significantly correlated with higher systolic BP among black men and women, but not white or Mexican-American participants. BLLs were significantly associated with higher diastolic BPs among white men and women and black men, whereas, a negative association was observed in Mexican-American men that had, also, a wider pulse pressure. Black men in the 90th percentile of blood lead distribution (BLL > 3.50 μg/dL) compared to black men in the 10th percentile of blood lead distribution (BLL < 0.7 μg/dL) had a significant increase of risk of having hypertension (adjusted POR=2.69; 95% CI: 1.08-6.72). In addition, blood cadmium was significantly associated with hypertension and systolic and diastolic blood. This study found that, despite the continuous decline in blood lead in the U.S. population, lead exposure disparities among race and gender still exist.
机译：这项研究调查了低血铅水平（≤10μg/ dL）是否与血压（BP）结果相关。作者分析了1999-2006年美国国家健康和营养检查调查以及年龄在20岁以上的参与者的数据。结果变量是收缩压和舒张压测量值，脉压和高血压状态。进行了按种族/民族和性别分层的多变量线性和逻辑回归。黑人和女性的血铅水平（BLL）与较高的收缩压显着相关，而白人或墨西哥裔美国人则没有。 BLL与白人和白人以及黑人中较高的舒张压BP显着相关，而在脉搏压力也较宽的墨西哥裔美国人中观察到负相关。血铅分布第90个百分位数（BLL> 3.50μg/ dL）的黑人与血铅分布第10个百分位数（BLL <0.7μg/ dL）的黑人相比，患高血压的风险显着增加（POR调整后） = 2.69； 95％CI：1.08-6.72）。此外，血镉与高血压以及收缩期和舒张期血液显着相关。这项研究发现，尽管美国人群的血铅水平持续下降，但种族和性别之间的铅暴露差异仍然存在。

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  • 来源
    《Environmental research》 |2011年第8期|p.1249-1257|共9页
  • 作者

    Franco Scinicariello; Henry G. Abadin; H. Edward Murray;

  • 作者单位

    Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Division of Toxicology and Environmental Medicine, Atlanta, GA 30341, USA;

    Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Division of Toxicology and Environmental Medicine, Atlanta, GA 30341, USA;

    Centers for Disease Control and Prevention, Agency for Toxic Substances and Disease Registry, Division of Toxicology and Environmental Medicine, Atlanta, GA 30341, USA;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    blood lead; hypertension; blood pressure; NHANES; blood cadmium;

    机译：血铅高血压;血压;HAN血镉;

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