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The association between childhood asthma prevalence and monitored air pollutants in metropolitan areas, United States, 2001-2004

机译：美国大都市地区儿童哮喘患病率与监测的空气污染物之间的关联，2001-2004年

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摘要

Background: Air pollution exposure has been linked to adverse respiratory health outcomes among children, primarily in studies of acute exposures that are often in limited geographic areas. We sought to assess the association between chronic outdoor air pollution exposure, as measured by 12-month averages by county, and asthma among children in metropolitan areas across the nation. Methods: Eligible children included those aged 3-17 years residing in US metropolitan areas who were sampled in the 2001-2004 National Health Interview Survey (N=34,073). 12-month average air pollutant levels for sulfur dioxide, nitrogen dioxide, ozone and particulate matter were compiled by county for 2000-2004. Eligible children were linked to pollutant levels for the previous 12 months for their county of residence. Adjusted odds ratios of having current asthma or an asthma attack in the past 12 months were estimated in single pollutant logistic regression models.rnResults: Children in counties with ozone and, to a less consistent degree, particulate matter levels in the highest quartile were more likely to have current asthma and/or a recent asthma attack than children residing in counties with the lowest pollution levels; the adjusted odds for current asthma for the highest quartile of estimated ozone exposure was 1.56 (95% confidence interval [CI]: 1.15, 2.10) and for recent asthma attack 1.38 (95% CI: 0.99, 1.91). No associations were found with sulfur dioxide or nitrogen dioxide levels.rnConclusion: Although the current US standard for ozone is based on short-term exposure, this cross-sectional study suggests that chronic (12-month) exposure to ozone and particles is related to asthma outcomes among children in metropolitan areas throughout the US.
机译：背景：空气污染暴露已与儿童中不利的呼吸健康结果相关联，主要是在经常在有限地理区域内进行的急性暴露研究中。我们试图评估按县12个月平均值衡量的慢性室外空气污染暴露与全国大城市儿童哮喘之间的关系。方法：符合条件的儿童包括居住在美国大都市地区的3-17岁年龄段的儿童，这些儿童是在2001-2004年美国国家健康访问调查中抽样的（N = 34,073）。 2000-2004年，各县汇总了12个月的二氧化硫，二氧化氮，臭氧和颗粒物平均空气污染物水平。符合资格的儿童与他们居住所在县的前12个月的污染物水平相关。在单一污染物Logistic回归模型中估计了过去12个月中当前哮喘或哮喘发作的调整后优势比.rn结果：臭氧县的儿童和最高四分位数的颗粒物水平不太一致的可能性更大与居住在污染水平最低的县里的孩子相比，当前有哮喘和/或最近有哮喘发作；对于目前的哮喘，估计的最大臭氧暴露水平的调整后赔率是1.56（95％置信区间[CI]：1.15、2.10），而最近发生的哮喘发作的校正后赔率是1.38（95％CI：0.99、1.91）。没有发现与二氧化硫或二氧化氮含量有关联。rn结论：尽管当前的美国臭氧标准基于短期暴露，但这项横断面研究表明，长期（12个月）暴露于臭氧和颗粒物与全美大城市地区儿童的哮喘结局。

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  • 来源
    《Environmental research》 |2010年第3期|p.294-301|共8页
  • 作者

    Lara J. Akinbami; Courtney D. Lynch; Jennifer D. Parker; Tracey J. Woodruff;

  • 作者单位

    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA US Public Health Service, Rockville, MD, USA;

    Division of Epidemiology, The Ohio State University College of Public Health, Columbus, OH, USA;

    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA;

    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, Oakland, CA, USA;

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  • 正文语种 eng
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  • 关键词

    asthma; air pollution; children; epidemiology; public health;

    机译：哮喘;空气污染;孩子们流行病学公共卫生;

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