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首页> 外文期刊>Environmental Science & Technology >Transgenerational Proteome Plasticity in Resilience of a Marine Copepod in Response to Environmentally Relevant Concentrations of Microplastics
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Transgenerational Proteome Plasticity in Resilience of a Marine Copepod in Response to Environmentally Relevant Concentrations of Microplastics

机译：响应于环境相关浓度的微薄塑料，转基因蛋白质组可塑性在海洋桡足蛋白酶的弹性中

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摘要

Here, we examined the multigenerational effect of microplastics (6-mu m polystyrene beads; with different environmentally relevant concentrations of 0.023 and 0.23 mg/L in seawater) on the marine copepod Tigriopus japonicus under two-generation exposure (F0-F1) followed by one-generation recovery (F2) in clean seawater. Also, the seven life-history traits (survival, sex ratio, developmental time of nauplius phase, developmental time to maturation, number of clutches, number of nauplii/clutch, and fecundity) were measured for each generation. Furthermore, to investigate within-generation proteomic response and transgenerational proteome plasticity, proteome profiling was conducted for the F1 and F2 copepods under the control and 0.23 mg/L microplastics treatment. The results showed successful ingestion of microplastics in F0-F1 under both exposure concentrations, while higher concentration (0.23 mg/L) of microplastics resulted in the significant reduction in survival rate, number of nauplii/clutch, and fecundity. However, the affected traits were totally restored in the recovery generation (F2). Proteomic analysis demonstrated that microplastics exposure increased several cellular biosynthesis processes and, in turn, reduced energy storage due to the trade-off, hence compromising survival and reproduction of the treated copepods in F1. Interestingly, the two-generational effect of microplastics in copepods had significant transgenerational proteome plasticity as demonstrated by increased energy metabolism and stress-related defense pathway, which accounts for regaining of the compromised phenotypic traits during recovery (i.e., F2). Overall, this study provides a molecular understanding on the effect of microplastics at a translational level under long-term multigenerational exposure in marine copepods, and also .the transgenerational proteome plasticity is likely rendering the robustness of copepods in response to microplastics pollution.
机译：在这里，我们检查了微塑料（6-mu m聚苯乙烯珠子;在两代暴露（F0-F1）下的海洋Copepod tigriopus japonicus上的海水蛋白质蛋白水蛋白水蛋白水蛋白水蛋白（F0-F1）中的不同环境相关浓度为0.023和0.23mg / l的不同环境相关浓度。清洁海水中的一代恢复（F2）。此外，针对各一代测量测量每代测量每种一代测量每代测量的七种寿存，性别比率，Nauplius阶段的发育时间，成熟的发育时间，离合器数量，NauPlii /离合器的数量，融合的数量。此外，为了研究在内的蛋白质组学反应和转基因蛋白质组可塑性，在对照和0.23mg / L微薄的处理下进行F1和F2桡足蛋白酶进行蛋白质组分析。结果表明，在曝光浓度下，在F0-F1下，在F0-F1下进行微塑料的成功摄入，而较高的浓度（0.23mg / L）的微薄，导致存活率的显着降低，Nauplii /离合器和繁殖力。然而，受影响的性状在恢复生成（F2）中完全恢复。蛋白质组学分析表明，微塑料曝光增加了几种细胞生物合成过程，而且又降低了由于折衷而降低的能量存储，因此损害了F1中治疗的桡足蛋白酶的存活率和再现。有趣的是，微塑料在桡足类的两代效应具有显着的转基因蛋白质组可塑性，如增加的能量代谢和相关的防御途径所证明，其估算恢复恢复过程中的受损表型性状（即，F2）。总体而言，本研究提供了关于在海洋桡足蛋白的长期多粒暴露下的转化水平的微塑料效果的分子理解，以及转基因蛋白质组可塑性可能使桡足污染的骨质蛋白的稳健性。

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  • 来源
    《Environmental Science & Technology》 |2019年第14期|8426-8436|共11页
  • 作者

    Zhang Chen; Jeong Chang-Bum; Lee Jae-Seong; Wang Dazhi; Wang Minghua;

  • 作者单位

    Xiamen Univ Coll Environm & Ecol State Key Lab Marine Environm Sci Xiamen 361102 Fujian Peoples R China;

    Sungkyunkwan Univ Coll Sci Dept Biol Sci Suwon 16419 South Korea;

    Sungkyunkwan Univ Coll Sci Dept Biol Sci Suwon 16419 South Korea;

    Xiamen Univ Coll Environm & Ecol State Key Lab Marine Environm Sci Xiamen 361102 Fujian Peoples R China;

    Xiamen Univ Coll Environm & Ecol State Key Lab Marine Environm Sci Xiamen 361102 Fujian Peoples R China|Xiamen Univ Fujian Prov Key Lab Coastal Ecol & Environm Studi Xiamen 361102 Fujian Peoples R China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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