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Quantitative Microbial Risk Assessment and Molecular Biology: Paths to Integration

机译:定量微生物风险评估和分子生物学:集成的路径

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摘要

Quantitative microbial risk assessment (QMRA) has now been in use for over 35 years and has formed the basis for developing criteria for ensuring public health related to water, food, and remediation, to name a few areas. The initial data for QMRA (both in exposure assessment and in dose response assessment) came from measurements using assays for viability, such as plate counts, plaque assays, or animal infectivity. With the increasing use of molecular methods for the measurement of microorganisms in the environment, it has become important to assess how to use such data to estimate infectious disease risks. The limitations to the use of such data and needs to resolve the limitations will be addressed.
机译:定量微生物风险评估(QMRA)现已使用超过35年,已为确保与水,食品和修复有关的公共卫生的标准制定标准的基础,以命名几个地区。 QMRA的初始数据(在暴露评估和剂量响应评估中)来自使用用于活力的测定的测量,例如板数,斑块测定或动物感染性。随着越来越多的使用分子方法来测量环境中的微生物,评估如何使用这些数据来估计传染病风险变得重要。将解决这些数据的限制,并需要解决限制。

著录项

  • 来源
    《Environmental Science & Technology》 |2020年第14期|8539-8546|共8页
  • 作者

    Charles N. Haas;

  • 作者单位

    Department of Civil Architectural & Environmental Engineering Drexel University Philadelphia Pennsylvania 19104 United States;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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