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首页> 外文期刊>Environmental Science & Technology >Linkage between Particulate Matter Properties and Lung Function in Schoolchildren: A Panel Study in Southern China
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Linkage between Particulate Matter Properties and Lung Function in Schoolchildren: A Panel Study in Southern China

机译：学童颗粒物质与肺功能之间的联系：中国南方的小组研究

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摘要

While several scientific studies have linked PM_(2.5) to decreased lung function, there is still some degree of uncertainty regarding which particulate physicochemical properties are most harmful. We followed a panel of 57 healthy schoolchildren (857 person-days) to investigate the associations between a wide variety of PM_(2.5) and lung function in Heshan, China in 2016 for three periods. We monitored the daily concentrations of mass, chemical composition, size, number, surface area, and volume of particulate mixture. Associations of lung function with various particle metrics were estimated using generalized estimating equations and unconstrained distributed lag models. Random forest model was used to compare the relative importance of exposure metrics. Immediate (lag 0) associations of PM_(2.5) and carbonaceous aerosols with reduced FEV_1 and MMEF, and accumulation-mode particles with FEV_1 were found. Slightly delayed (lag 1, 2) effects on PEF were particularly prominent for Aitken-mode particles. Possible cumulative (lags 0-2) effects of PM_(2.5) and carbonaceous aerosols on PEF and Aitken-mode particles on FEV_1, MMEF, and PEF were observed. This study provides comprehensive evidence that the physicochemical properties of particulate mixtures are associated with reduced lung function in children. Organic carbon (OC) may be an important risk factor for the decreased lung function related to PM exposure.
机译：虽然几个科学研究已经将PM_（2.5）联系起来降低肺功能，但仍然存在一定程度的不确定性，关于哪种颗粒物理化学性质最有害。我们遵循57名健康学童（857人）的小组，调查2016年河山各种PM_（2.5）和肺功能之间的协会。我们监测了每日浓度的质量，化学成分，大小，表面积和颗粒混合物的体积。使用广义估计方程和无约束分布式滞后模型估计肺功能与各种粒度指标的关联。随机森林模型用于比较曝光度量的相对重要性。发现PM_（2.5）和具有减少的FEV_1和MMEF的碳质气溶胶和具有FEV_1的累积模式颗粒的碳质气溶胶的立即（LAG 0）。对PEF的稍微延迟（LAG 1,2）对AITKEN模式颗粒特别突出。观察到PM_（2.5）和PEF和AITKEN模式颗粒上的PM_（2.5）和碳质气溶胶上的可能累积（滞后0-2）的效果在FEV_1，MMEF和PEF上进行。本研究提供了综合证据，即颗粒混合物的物理化学特性与儿童的肺功能降低有关。有机碳（OC）可能是与PM暴露有关的肺功能下降的重要危险因素。

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  • 来源
    《Environmental Science & Technology》 |2020年第15期|9464-9473|共10页
  • 作者

    Qiansheng Hu; Xiaoyan Ma; Dingli Yue; Jiajia Dai; Lu Zhao; Dan Zhang; Deji Ciren; Jianqing Lin; Boning You; Yuhong Zhai; Luan Yuan; Weiwei Lin;

  • 作者单位

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Guangdong Environmental Monitoring Center State Environmental Protection Key Laboratory of Regional Air Quality Monitoring Guangzhou 510308 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

    Guangdong Environmental Monitoring Center State Environmental Protection Key Laboratory of Regional Air Quality Monitoring Guangzhou 510308 P. R. China;

    Guangdong Environmental Monitoring Center State Environmental Protection Key Laboratory of Regional Air Quality Monitoring Guangzhou 510308 P. R. China;

    Department of Occupational and Environmental Health School of Public Health Sun Yat-Sen University Guangzhou 510080 P. R. China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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