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首页> 外文期刊>Environmental Science & Technology >Urinary Concentrations of Bisphenols and Their Association with Biomarkers of Oxidative Stress in People Living Near E-Waste Recycling Facilities in China
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Urinary Concentrations of Bisphenols and Their Association with Biomarkers of Oxidative Stress in People Living Near E-Waste Recycling Facilities in China

机译：中国电子垃圾回收设施附近居民中双酚的尿液浓度及其与氧化应激生物标志物的关系

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摘要

In this study, concentrations of bisphenol A (BPA) and seven other bisphenols (BPs) were measured in urine samples collected from people living in and around e-waste dismantling facilities, and in matched reference population from rural and urban areas in China. BPA, bisphenol S (BPS), and bisphenol F (BPF) were frequently detected (detection frequencies: ＞ 90%) in urine samples collected from individuals who live near e-waste facilities, with geometric mean (GM) concentrations of 2.99 (or 3.75), 0.361 (or 0.469), and 0.349 (or 0.435) ng/ mL (or μg/g Cre), respectively; the other five BPs were rarely round in urine samples, regardless of the sampling location. The urinary concentrations of BPA and BPF, but not BPS, were significantly higher in individuals from e-waste recycling locations than did individuals from a rural reference location. Our findings indicated that e-waste dismantling activities contribute to human exposure to BPA and BPF. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) was measured in urine as a marker of oxidative stress. In the e-waste dismantling location, urinary 8-OHdG was significantly and positively correlated (p ＜ 0.001) with urinary BPA and BPS, but not BPF; a similar correlation was also observed in reference sites. These findings suggest that BPA and BPS exposures are associated with elevated oxidative stress.
机译：在这项研究中，测量了从生活在电子废物拆解设施内和附近的人们以及中国农村和城市地区的匹配参考人群收集的尿液样本中的双酚A（BPA）和其他七种双酚（BPs）的浓度。在居住于电子废物处理设施附近的人的尿液样本中经常检测到BPA，双酚S（BPS）和双酚F（BPF）（检测频率：＞ 90％），几何平均（GM）浓度为2.99（或3.75），0.361（或0.469）和0.349（或0.435）ng / mL（或μg/ g Cre）；不论采样位置如何，其他五个BP在尿液样本中很少是圆形的。来自电子废物回收地点的个人的尿中BPA和BPF浓度而非BPS显着高于农村参考地点的个人。我们的发现表明，电子废物的分解活动会导致人类接触BPA和BPF。在尿液中测量了8-Hydroxy-2'-deoxyguanosine（8-OHdG）作为氧化应激的标志。在电子废物分解地点，尿中的8-OHdG与尿中的BPA和BPS呈显着正相关（p ＜0.001），而与BPF没有显着正相关。在参考部位也观察到类似的相关性。这些发现表明，BPA和BPS暴露与氧化应激升高有关。

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  • 来源
    《Environmental Science & Technology》 |2016年第7期|4045-4053|共9页
  • 作者

    Tao Zhang; Jingchuan Xue; Chuan-zi Gao; Rong-liang Qiu; Yan-xi Li; Xiao Li; Ming-zhi Huang; Kurunthachalam Kannan;

  • 作者单位

    School of Environmental Science and Engineering, Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Sun Yat-sen University, Guangzhou 510275, People's Republic of China;

    Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Albany, New York 12201, United States;

    School of Environmental Science and Engineering, Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Sun Yat-sen University, Guangzhou 510275, People's Republic of China;

    School of Environmental Science and Engineering, Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Sun Yat-sen University, Guangzhou 510275, People's Republic of China;

    School of Environmental Science and Engineering, Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Sun Yat-sen University, Guangzhou 510275, People's Republic of China;

    School of Environmental Science and Engineering, Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Sun Yat-sen University, Guangzhou 510275, People's Republic of China;

    Department of Water Resources and Environment, Guangdong Provincial Key Laboratory of Urbanization and Geo-simulation, Sun Yat-sen University, Guangzhou 510275, Peopl's Republic of China;

    Wadsworth Center, New York State Department of Health, and Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Albany, New York 12201, United States,Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 22252, Saudi Arabia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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