• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Environmental Science & Technology >Relationships between Antibiotics and Antibiotic Resistance Gene Levels in Municipal Solid Waste Leachates in Shanghai, China
【24h】

Relationships between Antibiotics and Antibiotic Resistance Gene Levels in Municipal Solid Waste Leachates in Shanghai, China

机译：上海市城市生活垃圾渗滤液中抗生素与耐药基因水平的关系

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Many studies have quantified antibiotics and antibiotic resistance gene (ARG) levels in soils, surface waters, and waste treatment plants (WTPs). However, similar work on municipal solid waste (MSW) landfill leachates is limited, which is concerning because antibiotics disposal is often in the MSW stream. Here we quantified 20 sulfonamide (SA), quinolone (FQ), tetracycline (TC), macrolide (ML), and chloramphenicol (CP) antibiotics, and six ARGs (sul1, sul2, tetQ, tetM, ermB, and mefA) in MSW leachates from two Shanghai transfer stations (TS; sites Hulin (HL) and Xupu (XP)) and one landfill reservoir (LR) in April and July 2014. Antibiotic levels were higher in TS than LR leachates (985 ± 1965 ng/L vs 345 ± 932 ng/L, n = 40), which was because of very high levels in the HL leachates (averaging at 1676 ± 5175 ng/L, n = 40). The mean MLs (3561 ± 8377 ng/L, n = 12), FQs (975 ± 1608 ng/L, n = 24), and SAs (402 ± 704 ng/L, n = 42) classes of antibiotics were highest across all samples. ARGs were detected in all leachate samples with normalized sull and ermB levels being especially elevated (-1.37 ± 1.2 and -1.76 ± 1.6 log (copies/16S-rDNA), respectively). However, ARG abundances did not correlate with detected antibiotic levels, except for tetW and tetQ with TC levels (r = 0.88 and 0.81, respectively). In contrast, most measured ARGs did significantly correlate with heavy metal levels (p ＜ 0.05), especially with Cd and Cr. This study shows high levels of ARGs and antibiotics can prevail in MSW leachates and landfills may be an underappreciated as a source of antibiotics and ARGs to the environment.
机译：许多研究已经量化了土壤，地表水和废物处理厂（WTP）中的抗生素和抗生素抗性基因（ARG）水平。但是，市政固体垃圾填埋场渗滤液的类似工作是有限的，这是令人担忧的，因为MSW流中经常会处理抗生素。在这里，我们对MSW中的20种磺酰胺（SA），喹诺酮（FQ），四环素（TC），大环内酯（ML）和氯霉素（CP）抗生素以及6种ARG（sul1，sul2，tetQ，tetM，ermB和mefA）进行了定量。 2014年4月和2014年7月，来自两个上海转运站（TS；虎林（HL）和Xu浦（XP）站点）和一个垃圾填埋场（LR）的渗滤液。TS中的抗生素含量高于LR渗滤液（985±1965 ng / L vs 345±932 ng / L，n = 40），这是因为HL渗滤液中的含量很高（平均为1676±5175 ng / L，n = 40）。平均ML（3561±8377 ng / L，n = 12），FQ（975±1608 ng / L，n = 24）和SAs（402±704 ng / L，n = 42）最高所有样本。在所有渗滤液样品中均检测到ARGs，标准化的sull和ermB水平特别高（分别为-1.37±1.2和-1.76±1.6 log（份数/ 16S-rDNA））。但是，除了tetW和tetQ的TC水平外，ARG的丰度与检测到的抗生素水平无关（分别为r = 0.88和0.81）。相反，大多数测得的ARGs确实与重金属水平显着相关（p ＜0.05），尤其是Cd和Cr。这项研究表明，在城市固体垃圾渗滤液中，高含量的ARGs和抗生素可能普遍存在，而垃圾填埋场作为环境中抗生素和ARGs的来源可能未被充分认识。

著录项

  • 来源
    《Environmental Science & Technology》 |2015年第7期|4122-4128|共7页
  • 作者

    Dong Wu; Zhiting Huang; Kai Yang; David Graham; Bing Xie;

  • 作者单位

    Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, School of Ecological and Environmental Science, East China Normal University, Shanghai 200241, China;

    Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, School of Ecological and Environmental Science, East China Normal University, Shanghai 200241, China;

    Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, School of Ecological and Environmental Science, East China Normal University, Shanghai 200241, China;

    School of Civil Engineering and Geosciences, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom;

    Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, School of Ecological and Environmental Science, East China Normal University, Shanghai 200241, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号