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Levels of Polychlorinated Biphenyls in Human Adipose Tissue Samples from Southeast China

机译：来自中国东南部的人体脂肪组织样品中的多氯联苯含量

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摘要

This paper presents a comprehensive study of polychlorinated biphenyl (PCB) levels and homologue profiles in human adipose tissues among residents of Southeast China. A large number of samples (n = 303) were selected for a number of PCB congeners (n = 62) which were analyzed by highly sensitive gas chromatography-tandem mass spectrometry (GC-MS/MS). The total mean PCB concentrations were 27.2 μg/kg fat (n = 159) in Anhui Province and 17.2μg/kg fat (n = 144) in Jiangsu Province. A significant correlation was observed between age and PCB levels but not found between gender and PCB levels. The relationship between the environmental contaminant levels and the PCB concentration in adipose tissue was also investigated. It was found that the higher PCB concentrations in human adipose tissue were associated with the higher environmental PCB levels in the corresponding regions. The PCB homologue profiles of the human adipose tissue in China are different from those in the world, similarly to the different PCB homologue pattern between Chinese and global soils. The concept of the urban fractionanon effect in the environment may be applicable to explain the PCB homologue profiles and PCB levels in the human adipose tissues collected from different provinces in China. The data presented in this study can provide useful information on human exposures to PCBs in the general population of Southeast China.
机译：本文对中国东南部居民的人体脂肪组织中多氯联苯（PCB）的水平和同系物谱进行了全面的研究。选择了许多PCB同类物（n = 62）的大量样品（n = 303），并通过高灵敏度气相色谱-串联质谱（GC-MS / MS）进行了分析。安徽省的PCB平均总浓度为27.2μg/ kg脂肪（n = 159），江苏省为17.2μg/ kg脂肪（n = 144）。年龄和多氯联苯含量之间存在显着的相关性，而性别和多氯联苯含量之间无明显相关性。还研究了环境污染物水平与脂肪组织中PCB浓度之间的关系。发现在人体脂肪组织中较高的PCB浓度与相应区域中较高的环境PCB水平有关。中国人类脂肪组织的PCB同源物谱与世界不同，这与中国和全球土壤之间的PCB同源物模式相似。环境中城市分数效应的概念可能适用于解释从中国不同省份采集的人体脂肪组织中的PCB同源物概况和PCB水平。这项研究中提供的数据可以提供有关中国东南部普通人群中人接触多氯联苯的有用信息。

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  • 来源
    《Environmental Science & Technology》 |2010年第11期|P.4334-4340|共7页
  • 作者

    NA WANG; DEYANG KONG; DAOJI CAI; LILI SHI; YANZHONG CAO; GUOFANG PANG; RONGBIN YU;

  • 作者单位

    Nanjing Institute of Environmental Science, Ministry of Environmental Protection of China, Nanjing 210042, China Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection of China, Nanjing 210042, China;

    rnNanjing Institute of Environmental Science, Ministry of Environmental Protection of China, Nanjing 210042, China Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection of China, Nanjing 210042, China;

    rnNanjing Institute of Environmental Science, Ministry of Environmental Protection of China, Nanjing 210042, China Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection of China, Nanjing 210042, China;

    rnNanjing Institute of Environmental Science, Ministry of Environmental Protection of China, Nanjing 210042, China Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection of China, Nanjing 210042, China;

    rnTechnological Center of Qin Huangdao Entry-Exit Inspection and Quarantine Bureau, Qinhuangdao 066002, China;

    rnTechnological Center of Qin Huangdao Entry-Exit Inspection and Quarantine Bureau, Qinhuangdao 066002, China;

    rnDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 210029, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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