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首页> 外文期刊>Environmental toxicology and chemistry >RESPONSE OF AEDES AEGYPTI (DIPTERA: CULICIDAE) LARVAE TO THREE XENOBIOTIC EXPOSURES: LARVAL TOLERANCE AND DETOXIFYING ENZYME ACTIVITIES
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RESPONSE OF AEDES AEGYPTI (DIPTERA: CULICIDAE) LARVAE TO THREE XENOBIOTIC EXPOSURES: LARVAL TOLERANCE AND DETOXIFYING ENZYME ACTIVITIES

机译：埃及伊蚊幼虫对三种异物暴露的反应：幼虫耐受性和解毒酶活性

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摘要

The ability of mosquito larvae to tolerate toxic compounds (temephos, Bacillus thuringiensis var. israelensis, toxic vegetable leaf litter) was examined on a laboratory larval strain of Aedes aegypti L. Bioassays and detoxifying enzyme activity measurements were performed to compare tolerance/resistance capacities. The possibility of a functional plasticity of detoxifying equipment was investigated through experimental determination of the inductive effect of each xenobiotic within a given generation. In the same way, the selective effect of a toxic leaf litter was also investigated along successive generations. Results revealed that differential cytochrome P450 monooxygenase, esterase, and glutathione S-transferase activity levels correlated with the bioassay results. Both induction and selection increased larval tolerance to the xenobiotics used and increased the levels of larval detoxifying enzyme activities.
机译：在埃及伊蚊的实验室幼虫菌株上检查了蚊虫幼虫对有毒化合物（temephos，苏云金芽孢杆菌变种israelensis，有毒蔬菜叶凋落物）的耐受能力。进行了生物测定和解毒酶活性测定，以比较耐受/耐药能力。通过实验确定给定世代中每种异生素的诱导作用，研究了排毒设备功能可塑性的可能性。同样，还研究了有毒叶片凋落物的选择性效应。结果显示差异细胞色素P450单加氧酶，酯酶和谷胱甘肽S-转移酶活性水平与生物测定结果相关。诱导和选择都增加了对所用异种生物的幼虫耐受性，并增加了幼虫解毒酶活性的水平。

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