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Multimedia persistence as an indicator of potential for population-level intake of environmental contaminants.

机译:多媒体持久性可作为潜在的人口一级环境污染物摄入指标。

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Although intuitively it is apparent that population-level exposure to contaminants dispersed in the environment must be related to the persistence of the contaminant, there has been little effort to quantify this link formally. In this paper we investigate the relationship between overall persistence and/or overall residence time in a multimedia exposure environment and the population-level intake of contaminants as expressed by intake fraction (iF), the cumulative fraction of chemical emitted to the environment that is taken up by members of the population. We demonstrate that for any given contaminant and emission scenario the definition of iF implies that it is directly proportional to the overall multimedia persistence (Pov), or the overall multimedia residence time (Tov). The proportionality constant has dimensions of time and represents the characteristic time for population intake (CTI) of the chemical from the environment. We then apply the CalTOX fate and exposure model to explore how Tov and CTI combine to determine the magnitude of iF We find that CTI has a narrow range of possible values relative to Tov across multiple chemicals and emissions scenarios. We use data from the Canadian Environmental Protection Act Priority Substance List (PSL1) Assessments and multimedia Pov to show that exposure assessments based on empirical observation are consistent with interpretations from the model. Results indicate that Pov derived from screening-level assessments of persistence, bioaccumulation potential, and toxicity (PBT) is a useful indicator of the potential for population-level exposure.
机译:尽管从直观上看,很明显人口水平暴露于环境中的污染物必定与污染物的持久性有关,但很少有人努力正式量化这一联系。在本文中,我们研究了在多媒体暴露环境中的总体持久性和/或总体停留时间与污染物的总体水平摄入之间的关系,以摄入量(iF)表示,即排放到环境中的化学物质的累积量由人口组成。我们证明,对于任何给定的污染物和排放情景,iF的定义意味着它与总体多媒体持久性(Pov)或总体多媒体停留时间(Tov)成正比。比例常数具有时间维度,代表从环境中化学物质的总体摄入量(CTI)的特征时间。然后,我们使用CalTOX命运和暴露模型来探索Tov和CTI如何结合以确定iF的大小。我们发现,在多种化学物质和排放情景下,CTI相对于Tov而言具有较小的可能值范围。我们使用《加拿大环境保护法》优先物质清单(PSL1)评估和多媒体Pov中的数据来表明,基于经验观察的暴露评估与该模型的解释一致。结果表明,从持久性,生物蓄积性和毒性(PBT)的筛查水平评估中得出的Pov是潜在的人群水平接触指标。

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