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首页> 外文期刊>Environmental toxicology and chemistry >CHARACTERISTICS OF IMIDACLOPRID TOXICITY IN TWO APIS MELLIFERA SUBSPECIES
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CHARACTERISTICS OF IMIDACLOPRID TOXICITY IN TWO APIS MELLIFERA SUBSPECIES

机译：两种APIs MELLIFERA亚种的吡虫啉毒性特征

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摘要

Imidacloprid (l-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine) belongs to a new chemical family of chloronicotinyl compounds whose mode of action on the insect nervous system differs from that of traditional neurotoxic products. Imidacloprid, a strong systemic compound, is effective against several sucking and mining pests. The acute toxicity of contact and oral applications on two Apis mellifera subspecies, Apis mellifera mellifera and Apis mellifera caucasica, was investigated. In all toxicological studies, each dose included three cages of 20 individuals and each study was replicated three times. The dose-mortality relation revealed some unusual characteristics. At low imidacloprid concentrations, a biphasic mortality appeared, particularly with the contact exposure route. At moderate doses, mortality profiles at 24 and 48 h were different only after oral application. Response kinetics showed that mortality was delayed at the higher doses of imidacloprid. After oral intoxication, the LD50 values of imidacloprid at 24 and 48 h were about 5 ng/bee for both A. m. mellifera and A. m. caucasica. After contact application, the LD50 values at 24 and 48 h were approximately 24 ng/bee for A. m. mellifera and 14 ng/bee for A. m. caucasica. Imidacloprid ranks among the more potent contact insecticides in this important pollinator species.
机译：吡虫啉（1-（6-氯-3-吡啶基甲基）-N-硝基咪唑烷基-2-亚胺基胺）属于氯烟碱化合物的新化学家族，其对昆虫神经系统的作用方式不同于传统的神经毒性产品。吡虫啉是一种强系统性化合物，可有效抵抗多种吮吸和开采害虫。研究了接触和口服施用对两个Apis mellifera亚种，Apis mellifera mellifera和Apis mellifera caucasica的急性毒性。在所有毒理学研究中，每个剂量均包括三个笼子，每组20个个体，每个研究重复三次。剂量-死亡率关系显示出一些不寻常的特征。在吡虫啉浓度低时，出现双相死亡率，尤其是接触接触途径时。在中等剂量下，仅在口服后24和48 h的死亡率曲线是不同的。响应动力学表明，吡虫啉高剂量可延缓死亡率。口服中毒后，A。m。的吡虫啉在24和48 h的LD50值约为5 ng / bee。 mellifera和A. m。高加索。接触应用后，A。m在24和48 h的LD50值约为24 ng / bee。 mellifera和A. m。的14 ng / bee高加索。吡虫啉在该重要的传粉媒介物种中属于更有效的接触杀虫剂。

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