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首页> 外文期刊>Experimental Animals >A Case of Fibrosarcoma on the Perivertebral Surface of a Ferret with Hind Limb Paralysis
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A Case of Fibrosarcoma on the Perivertebral Surface of a Ferret with Hind Limb Paralysis

机译：雪貂后肢瘫痪椎体表面纤维肉瘤一例

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摘要

A 2.5 year-old female ferret had a stiff palpable mass arising from the dorsal surface of the thoracic (T) to lumbar (L) vertebrae with paralysis of the hind limbs. By myelography the dorsal and ventral lines of contrast were not observed in the area forwarded of L3. Grossly, the tumor encircled the dorsal vertebrae. Microscopically, tumor cells were proliferated intimately and were attached to the vertebrae surface involving surrounding fatty and connective tissues. The tumor consisted of fibroblastic cells with prominent cellular atypia. The bromodeoxyuridine (BrdU) labeling index to examine cellular kinetics was high (11.8%). Based on macro and micropathological features, the present tumor was diagnosed as periosteal fibrosarcoma arising from perivertebral connective tissue.
机译：一个2.5岁的雌性雪貂的硬性明显肿块是由胸椎（T）到腰椎（L）的背表面伴有后肢麻痹引起的。通过脊髓造影，在L3向前的区域中未观察到背侧和腹侧的对比线。大体上，肿瘤包围了背椎骨。在显微镜下，肿瘤细胞被紧密增殖并附着在椎骨表面，涉及周围的脂肪和结缔组织。肿瘤由具有明显细胞异型性的成纤维细胞组成。用于检查细胞动力学的溴脱氧尿苷（BrdU）标记指数很高（11.8％）。根据宏观和微观病理学特征，本肿瘤被诊断为由椎骨周围结缔组织引起的骨膜纤维肉瘤。

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