Correlation Between Body Weight (epididymal Fat) And Permeation Rate Of Serum Leptin Through The Blood-brain Barrier (bbb) In Male Rats Aged 8 Months

Mitsuro SUZUKI; Qing DING; Shiro MURANAKA; Megumi KIGURE; Masaaki KOJIMA; Misao TERADA; Noyuri KATAOKA; Akiko HAGIWARA; Pudcharaporn KROMKHUN; Naoki MORITANI; Haruo HASHIMOTO; Makoto YOKOSUKA; Fujiro SAKURAI; Minoru TANAKA; Toru R. SAITO

首页> 外文期刊>Experimental Animals >Correlation Between Body Weight (epididymal Fat) And Permeation Rate Of Serum Leptin Through The Blood-brain Barrier (bbb) In Male Rats Aged 8 Months

【24h】

Correlation Between Body Weight (epididymal Fat) And Permeation Rate Of Serum Leptin Through The Blood-brain Barrier (bbb) In Male Rats Aged 8 Months

机译：8个月龄雄性大鼠体重（附睾脂肪）与血清瘦素透过血脑屏障的渗透率的相关性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

In this study, in order to clarify the kinetics of leptin, we focused on the ratio of leptin concentrations in cerebrospinal fluid and serum in aged male rats, and examined the weight of epididymal fat, and the passage rate of leptin through the blood-brain barrier. In the lighter animals, the epididymal fat weight was low, while leptin concentrations in the serum and cerebrospinal fluid were also low. Conversely, in the heavier animals, the weight of epididymal fat and leptin concentrations in the serum and cerebrospinal fluid were higher. With regard to the ratio of leptin in the cerebrospinal fluid and serum, the passage rate of leptin through the blood-brain barrier was lower in the heavier animals than in the lighter animals.

机译：在这项研究中，为了阐明瘦素的动力学，我们集中于老年雄性大鼠脑脊液和血清中瘦素浓度的比率，并检查附睾脂肪的重量以及瘦素通过血脑的通过率。屏障。在较轻的动物中，附睾脂肪重量较低，而血清和脑脊髓液中的瘦素浓度也较低。相反，在较重的动物中，血清和脑脊液中附睾脂肪的重量和瘦素的浓度较高。关于瘦素在脑脊液和血清中的比例，较瘦的动物中瘦素通过血脑屏障的通过率较低。

著录项

来源
《Experimental Animals》 |2008年第5期|485-488|共4页
作者
Mitsuro SUZUKI; Qing DING; Shiro MURANAKA; Megumi KIGURE; Masaaki KOJIMA; Misao TERADA; Noyuri KATAOKA; Akiko HAGIWARA; Pudcharaporn KROMKHUN; Naoki MORITANI; Haruo HASHIMOTO; Makoto YOKOSUKA; Fujiro SAKURAI; Minoru TANAKA; Toru R. SAITO;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
bbb; FAT; leptin;

机译：bbb;FAT;瘦素;

相似文献

外文文献
中文文献
专利

1. The effect of blood-brain barrier (BBB)-specific laminins for barrier function with a new in vitro BBB model incorporating multi-culturing system of BBB components [J] . Y. Takeshita, S. Fujikawa, M. Omoto, Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology . 2017,第期

机译：血型脑屏障（BBB）特异性层压族屏障功能的影响，具有掺入BBB组分多培养系统的新型体外BBB模型
2. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice. [J] . Uchida Y, Ohtsuki S, Kamiie J, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2011,第2期

机译：血脑屏障（BBB）药动学：基于BBB转运蛋白的浓度，体外固有转运活性以及小鼠血浆和脑中未结合的部分，重建11种P-糖蛋白底物的体内脑分布。
3. Short-term treatment with metformin decreases serum leptin concentration without affecting body weight and body fat content in normal-weight healthy men. [J] . Fruehwald Schultes B, Oltmanns KM, Toschek B, Metabolism: Clinical and Experimental . 2002,第4期

机译：二甲双胍的短期治疗可降低血清瘦素浓度，而不会影响体重正常的健康男性的体重和体脂含量。
4. CONCENTRATIONS OF BOAR TAINT COMPOUNDS IN SURGICALLY CASTRATED, CRYPTORCHID AND NORMAL ENTIRE MALES AT 9 MONTHS OF AGE [C] . Stuart J. Andrews, Monica Giberti, Michele Apicella, Congress ofthe International Pig Veterinary Society . 2008

机译：在9个月的肠道阉割，Cryptorchid和正常整个男性的猪污染物浓度
5. Effects of a 3-Day High Fat vs High Carbohydrate Diet on Serum Leptin Levels, and Perceived Fatigue in Mild-to-Moderate Multiple Sclerosis [D] . DeSantis, Noelle. 2018

机译：3天高脂与高碳水化合物饮食对轻度至中度多发性硬化症患者血清瘦素水平和感知疲劳的影响
6. Puberty Is Delayed in Male Mice With Dextran Sodium Sulfate Colitis Out of Proportion to Changes in Food Intake Body Weight and Serum Levels of Leptin [O] . MARK D. DEBOER, YONGLI LI -1

机译：青春期延迟雄性小鼠葡聚糖硫酸钠结肠炎不成比例的变化食物摄入体重和瘦素的血清
7. Daily Melatonin Administration to Middle-Aged Male Rats Suppresses Body Weight, Intraabdominal Adiposity, and Plasma Leptin and Insulin Independent of Food Intake and Total Body Fat [O] . Wolden-Hanson, T, Mitton, D.R., McCants, R.L., 2000

机译：每天对中年雄性大鼠服用褪黑激素可抑制体重，腹内脂肪，血浆瘦素和胰岛素，而与食物摄入量和总脂肪无关
8. Daily Dermal Co-Exposure of Rats to DEET and Permethrin Produces Sensorimotor Deficit, and Changes in Blood-Brain Barrier (BBB) and Blood-Testis Barrier (BTB). [R] . Goldstein, L. B., Dechovskaia, A. M., Bullman, S., 2001

机译：每日皮肤暴露大鼠的DEET和氯菊酯产生感觉运动赤字，血脑屏障（BBB）和血睾屏障（BTB）的变化。

Correlation Between Body Weight (epididymal Fat) And Permeation Rate Of Serum Leptin Through The Blood-brain Barrier (bbb) In Male Rats Aged 8 Months

摘要

著录项

相似文献

相关主题

期刊订阅