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Analysis of novel Fraser syndrome mutant mouse that was found in ICR closed colony

机译:在ICR封闭菌落中发现的新型Fraser综合征突变小鼠的分析

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[Purpose] We have developed a system to find spontaneous mutations existing in an ICR closed colony. Using this system, we found an ICR No.78 carrying a novel spontaneous autosomal recessive mutation which is responsible for syndactyly of hindlimbs and cryptophthalmus. We report phenotypes of the abnormal mice and the responsible gene.
机译:[目的]我们已经开发出一种系统来发现ICR封闭菌落中存在的自发突变。使用该系统,我们发现ICR No.78携带了一种新的自发常染色体隐性突变,该突变可导致后肢和隐性眼球的合成。我们报告表型的异常小鼠和负责任的基因。

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