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Investigation of anesthetic agents for ketamine in rabbits

机译：兔氯胺酮麻醉剂的研究

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In animal experiments, animal anesthesia is one of a important item. In anesthesia of a rabbit, ketamine has been used well. However, as for the ketamine, use became difficult because it was appointed to a narcotic. We examined anesthesia of a substitute of ketamine in rabbits. Pentobarbital, butorphanol and medetomidine were used as tested anesthetic agents. About individual medicine, the degree of anesthesia was examined with time. Body temperature, heart rate, respiratory rate, dilation of a pupil and some reflection functions was examined, as an index of anesthesia, Pentobarbital and medetomidine exist sedative effects inconsiderably. Sedation and analgesic effect were recognized to some extent, as for the mixture dosage of medetomidine and butorphanol. However, the surgical anesthesia effect was not provided all. Pentobarbital is not recommended in anesthesia of a rabbit from a respect of the safety. Medetomidine and butorphanol are originally analgesia, sedatives. We review anesthetic agents and relation and dose of experiment treatments sequentially.
机译：在动物实验中，动物麻醉是重要的项目之一。在兔子的麻醉中，氯胺酮已被很好地使用。但是，氯胺酮由于被指定用于麻醉品而变得难以使用。我们检查了兔子体内氯胺酮替代品的麻醉。戊巴比妥，布托啡诺和美托咪定被用作麻醉药。关于个体用药，随着时间检查麻醉度。检查了体温，心率，呼吸频率，瞳孔的扩张和某些反射功能，因为麻醉的指标，戊巴比妥和美托咪定的镇静作用微乎其微。对于美托咪定和丁啡诺的混合剂量，镇静和镇痛作用得到了一定程度的认可。但是，手术麻醉效果并未全部提供。从安全性的角度考虑，不建议在兔的麻醉中使用戊巴比妥。美托咪定和布托啡诺最初是镇痛药，镇静剂。我们将依次审查麻醉剂和实验治疗的关系和剂量。

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