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Refined porcine follicle stimulating hormone promotes the responsiveness of rabbits to multiple-ovulation treatment

机译:精制的猪卵泡刺激素可促进家兔对多排卵治疗的反应

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摘要

We investigated whether refined follicle stimulating hormone (FSH) with only a little contaminating LH can promote the responsiveness of rabbits to multiple-ovulation treatment. One group of female rabbits was stimulated with refined porcine FSH (pFSH), an FSH source with low LH activity, and another group was treated with pFSH. The mean number of eggs recovered from donors stimulated with refined pFSH (27 +/- 3) was significantly greater (P < 0.05) than that with pFSH (20 +/- 2). Furthermore, the mean number of remaining follicles of donors stimulated with refined pFSH (19 +/- 4) was significantly greater (P < 0.05) than that with pFSH (12 +/- 1). To decrease the number of remaining follicles in donors treated with refined pFSH, the dose of human chorionic gonadotropin (hCG) was increased from 75 to 150. However, there were no differences in the numbers of eggs and remaining follicles. The results of the present study suggest that refined pFSH with little contaminating LH promotes the responsiveness of rabbits to multiple-ovulation treatment compared with pFSH.
机译:我们调查了仅含有少量LH的精制卵泡刺激素(FSH)是否可以促进家兔对多次排卵治疗的反应性。一组雌性兔子用精制猪FSH(pFSH)(一种LH活性低的FSH来源)刺激,另一组用pFSH治疗。从精制pFSH(27 +/- 3)刺激的供体中回收的平均卵数(p <0.05)明显大于pFSH(20 +/- 2)。此外,精制pFSH(19 +/- 4)刺激的供体的平均剩余卵泡数显着大于pFSH(12 +/- 1)的(P <0.05)。为了减少用精制pFSH处理的供体中剩余卵泡的数量,人绒毛膜促性腺激素(hCG)的剂量从75增加到150。但是,卵和剩余卵泡的数量没有差异。本研究的结果表明,与pFSH相比,精制的pFSH几乎不污染LH促进了兔子对多次排卵治疗的反应。

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