...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Experimental Brain Research >Cathodal transcranial direct current stimulation on posterior parietal cortex disrupts visuo-spatial processing in the contralateral visual field
【24h】

Cathodal transcranial direct current stimulation on posterior parietal cortex disrupts visuo-spatial processing in the contralateral visual field

机译：顶叶后皮质的经颅经颅直流电刺激破坏了对侧视野中的视觉空间加工

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Transcranial direct current stimulation (tDCS) has recently undergone a resurgence in popularity as a powerful tool to non-invasively manipulate brain activity. While tDCS has been used to alter functions tied to primary motor and visual cortices, its impact on extrastriate visual areas involved in visuo-spatial processing has not yet been examined. In the current study, we applied tDCS to the cat visuoparietal (VP) cortex and assayed performance in a paradigm designed to assess the capacity to detect, localize and orient to static targets appearing at different spatial eccentricities within the visual field. Real or sham cathodal tDCS was unilaterally applied to the VP cortex, and orienting performance was assessed during (online), immediately after (offline; Experiments 1 and 2), and 1 or 24 h after the end of the tDCS stimulation (Experiment 2). Performance was compared to baseline data collected immediately prior to stimulation. Real, but not sham, tDCS induced significant decreases in performance for static visual targets presented in the contrastimulated visual hemifield. The behavioral impact of tDCS was most apparent during the online and immediate offline periods. The tDCS effect decayed progressively over time and performance returned to baseline levels ∼60 min after stimulation. These results are consistent with the effects of both invasive and non-invasive deactivation methods applied to the same brain region, and indicate that tDCS has the potential to modify neuronal activity in extrastriate visual regions and to sculpt brain activity and behavior in normal and neurologically impaired subjects.
机译：经颅直流电刺激（tDCS）最近作为一种强大的工具以非侵入性方式操纵大脑活动而流行起来。尽管tDCS已被用于改变与初级运动和视觉皮层相关的功能，但尚未研究其对涉及视觉空间处理的超视域的影响。在当前的研究中，我们将tDCS应用到了猫的腹膜（VP）皮质，并以一种范式分析了性能，该范式旨在评估检测，定位和定向出现在视野内不同空间离心率的静态目标的能力。将真实或假阴极的tDCS单侧应用于VP皮层，并在（在线），紧接（离线;实验1和2）以及tDCS刺激结束后1或24小时（实验2）中评估定向性能。将性能与刺激前立即收集的基线数据进行比较。真实的但不是假的，tDCS导致在对比模拟视觉半场中呈现的静态视觉目标的性能显着下降。在联机和脱机期间，tDCS的行为影响最为明显。 tDCS效应随时间逐渐衰减，刺激后性能恢复至基线水平〜60分钟。这些结果与应用于同一大脑区域的侵入性和非侵入性失活方法的效果一致，并表明tDCS具有修饰极视区域的神经元活动以及雕刻正常和神经系统受损的大脑活动和行为的潜力。科目。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号