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Scotopic Sensitivity of Central Retina in Early Age-Related Macular Degeneration

机译：与年龄相关的黄斑变性中视网膜中央部位的角膜敏感性

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Purpose: To test scotopic sensitivity and investigate whether there is rod system dysfunction in the central retina in early age - related macular degeneration (AMD). Methods: Scotopic(450 nm stimulus) and photopic (white light stimulus) sensitivity in 24 patients with early AMD was measured at 81 loci in central 25° of retina, and compared with the age - match normal controls. Results: Mean scotopic sensitivity of AMD patients was significantly lower than that of the normal controls. The patients of reduced scotopic sensitivity were more than those of reduced photopic sensitivity. Scotopic sensitivity deficit decreased with increasing eccentricity with the greatest deficit was 2. 5° to 5.0°. Conclusions: Scotopic sensitivity was decreased in the early stage of AMD. The parafoveal rod cells were selectively damaged in AMD. Scotopic sensitivity testing in macula may be a useful tool to diagnose and measure the fundus dysfunction of AMD.
机译：目的：测试暗视敏感性并调查早年相关黄斑变性（AMD）在中央视网膜中是否存在视杆系统功能障碍。方法：在24个视网膜中央25度的81个位点上，对24例早期AMD患者的暗视点（450 nm刺激）和明视（白光刺激）敏感性进行了测量，并与年龄匹配的正常对照组进行了比较。结果：AMD患者的平均暗视敏感性明显低于正常对照组。暗视敏感性降低的患者多于视敏度降低的患者。偏心率增加时，宫位敏感性缺陷减少，最大缺陷为2。5°至5.0°。结论：AMD早期的隐位敏感性降低。在AMD中，小凹旁杆状细胞被选择性损伤。黄斑区的角膜突敏感性测试可能是诊断和测量AMD眼底功能障碍的有用工具。

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